Human Interferon beta ELISA Kit | MyBioSource MBS2882247 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Interferon beta ELISA Kit

catalog :

MBS2882247

quantity :

48-Strip-Wells

price :

305 USD

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS2882247

products type :

ELISA Kit

products full name :

Human Interferon beta ELISA Kit

products short name :

[Interferon beta]

products name syn :

[Interferon beta; IFN-beta; Fibroblast interferon; IFNB1; IFB; IFNB]

other names :

[interferon beta; Interferon beta; interferon beta; interferon, beta 1, fibroblast; Fibroblast interferon]

products gene name :

[IFNB1]

other gene names :

[IFNB1; IFNB1; IFB; IFF; IFNB; IFN-beta; IFB; IFNB; IFN-beta]

uniprot entry name :

IFNB_HUMAN

reactivity :

Human

sequence length :

187

specificity :

Recombinant and natural Human Interferon beta, IFN-beta

storage stability :

For long term storage, please store the entire kit at -20 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Tissue Homogenates, Cell Culture Supernates Or Other Biological Fluids.

products description :

Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids. Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.

ncbi gi num :

4504603

ncbi acc num :

NP_002167.1

ncbi gb acc num :

NM_002176.3

uniprot acc num :

P01574

ncbi mol weight :

22,294 Da

ncbi pathways :

Cellular Senescence Pathway (1270426); Cellular Responses To Stress Pathway (1270414); Chagas Disease (American Trypanosomiasis) Pathway (147809); Chagas Disease (American Trypanosomiasis) Pathway (147795); Cytokine Signaling In Immune System Pathway (1269310); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Cytokines And Inflammatory Response Pathway (198794); Cytosolic DNA-sensing Pathway (125137); Cytosolic DNA-sensing Pathway (124833)

ncbi summary :

This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq, Sep 2015]

uniprot summary :

IFNB1: Has antiviral, antibacterial and anticancer activities. Belongs to the alpha/beta interferon family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 9p21. Cellular Component: extracellular region; extracellular space. Molecular Function: chloramphenicol O-acetyltransferase activity; cytokine activity; interferon-alpha/beta receptor binding. Biological Process: adaptive immune response; B cell activation during immune response; B cell differentiation; B cell proliferation; blood coagulation; cell surface receptor linked signal transduction; cytokine and chemokine mediated signaling pathway; defense response to bacterium; defense response to virus; humoral immune response; innate immune response; natural killer cell activation; natural killer cell activation during immune response; negative regulation of T cell differentiation; negative regulation of viral genome replication; positive regulation of innate immune response; positive regulation of peptidyl-serine phosphorylation of STAT protein; positive regulation of transcription from RNA polymerase II promoter; regulation of MHC class I biosynthetic process; response to exogenous dsRNA; response to virus; T cell activation during immune response

size1 :

48-Strip-Wells

price1 :

305 USD

size2 :

96-Strip-Wells

price2 :

395

size3 :

5x96-Strip-Wells

price3 :

1615

size4 :

10x96-Strip-Wells

price4 :

2880

more info or order :

MyBioSource product webpage