Mouse High mobility group protein B1 ELISA Kit | MyBioSource MBS2882189 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse High mobility group protein B1 ELISA Kit

catalog :

MBS2882189

quantity :

48-Strip-Wells

price :

355 USD

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS2882189

products type :

ELISA Kit

products full name :

Mouse High mobility group protein B1 ELISA Kit

products short name :

[High mobility group protein B1]

products name syn :

[High mobility group protein B1; High mobility group protein 1; HMG-1; Hmgb1; Hmg-1; Hmg1]

other names :

[high mobility group protein B1; High mobility group protein B1; high mobility group protein B1; high mobility group box 1; High mobility group protein 1; HMG-1]

products gene name :

[Hmgb1]

other gene names :

[Hmgb1; Hmgb1; p30; Hmg1; HMG-1; SBP-1; Hmg-1; Hmg1; HMG-1]

uniprot entry name :

HMGB1_MOUSE

reactivity :

Mouse

sequence length :

215

storage stability :

For long term storage, please store the entire kit at -20 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Tissue Homogenates, Cell Culture Supernates Or Other Biological Fluids.

products description :

Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids. Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.

ncbi gi num :

926657659

ncbi acc num :

NP_001300823.1

ncbi gb acc num :

NM_001313894.1

uniprot acc num :

P63158

ncbi mol weight :

24,894 Da

ncbi pathways :

Activated TLR4 Signalling Pathway (1323703); Activation Of DNA Fragmentation Factor Pathway (1323554); Advanced Glycosylation Endproduct Receptor Signaling Pathway (1323722); Apoptosis Pathway (1323524); Apoptosis Induced DNA Fragmentation Pathway (1323553); Apoptotic Execution Phase Pathway (1323548); Base Excision Repair Pathway (83240); Base Excision Repair Pathway (451); Cytosolic Sensors Of Pathogen-associated DNA Pathway (1323730); DEx/H-box Helicases Activate Type I IFN And Inflammatory Cytokines Production Pathway (1323738)

ncbi summary :

This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]

uniprot summary :

HMGB1: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells. Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2. Belongs to the HMGB family. Protein type: Nuclear receptor co-regulator; DNA repair, damage. Cellular Component: cytoplasm; extracellular space; neuron projection; nucleus. Molecular Function: bent DNA binding; crossed form four-way junction DNA binding; cytokine activity; open form four-way junction DNA binding; protein kinase activator activity. Biological Process: DNA geometric change; eye development; induction of positive chemotaxis; lung development; positive regulation of cell migration; positive regulation of glycogen catabolic process; positive regulation of mesenchymal cell proliferation; positive regulation of mitotic cell cycle; positive regulation of myeloid cell differentiation; positive regulation of protein amino acid phosphorylation; positive regulation of transcription from RNA polymerase II promoter; response to glucocorticoid stimulus

size1 :

48-Strip-Wells

price1 :

355 USD

size2 :

96-Strip-Wells

price2 :

475

size3 :

5x96-Strip-Wells

price3 :

2030

size4 :

10x96-Strip-Wells

price4 :

3700

more info or order :

MyBioSource product webpage