ELISA/assay

Mouse Low affinity immunoglobulin gamma Fc region receptor III ELISA Kit

MBS288193

48-Strip-Wells

355 USD

ELISA Kit

Mouse Low affinity immunoglobulin gamma Fc region receptor III ELISA Kit

[Low affinity immunoglobulin gamma Fc region receptor III]

[Low affinity immunoglobulin gamma Fc region receptor III; Low affinity immunoglobulin gamma Fc region receptor III; low affinity immunoglobulin gamma Fc region receptor III; Fc receptor, IgG, low affinity III; Fc-gamma RIII; FcRIII; CD_antigen: CD16]

[Fcgr3]

[Fcgr3; Fcgr3; CD16; IgG Fc receptor III; FcRIII]

FCGR3_MOUSE

Mouse

250

For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Assay Type: Sandwich. Detection Range: 0.312-20 ng/ml. Sensitivity: 0.19 ng/mL

Intra-Assay CV: <=6.4%. Inter-Assay CV: <=9.2%. Recovery: 101%

Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids. Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.

119877

P08508.1

P08508

30,036 Da

Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway (1323740); Immune System Pathway (1323639); Innate Immune System Pathway (1323671); Leishmaniasis Pathway (144183); Leishmaniasis Pathway (144028); Osteoclast Differentiation Pathway (193149); Osteoclast Differentiation Pathway (193096); Phagosome Pathway (153914); Phagosome Pathway (153859); Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway (1323741)

FCGR2A: low affinity receptor for the Fc region of IgGs. Binding to IgG initiates cellular responses against pathogens and soluble antigens. A type I membrane protein found on monocytes, neutrophils and platelets. SHP-1 associates with this protein to modulate signaling events in myeloid cells. Protein type: Receptor, misc.; Cell surface; Membrane protein, integral. Cellular Component: external side of plasma membrane; integral to membrane; membrane; plasma membrane. Molecular Function: IgG binding; IgG receptor activity. Biological Process: antibody-dependent cellular cytotoxicity; antigen processing and presentation of exogenous peptide antigen via MHC class I; cell surface receptor linked signal transduction; mast cell activation; neutrophil chemotaxis; phagocytosis, engulfment; phagocytosis, recognition; positive regulation of phagocytosis; positive regulation of tumor necrosis factor biosynthetic process; positive regulation of type I hypersensitivity; positive regulation of type IIa hypersensitivity; positive regulation of type III hypersensitivity; regulation of immune response; serotonin secretion

48-Strip-Wells

355 USD

96-Strip-Wells

475

5x96-Strip-Wells

2030

10x96-Strip-Wells

3700