catalog number :
MBS2881819
products type :
ELISA Kit
products full name :
Mouse Fibroblast growth factor 15 ELISA Kit
products short name :
[Fibroblast growth factor 15]
products name syn :
[Fibroblast growth factor 15; FGF-15; Fgf15]
other names :
[fibroblast growth factor 15; Fibroblast growth factor 15; fibroblast growth factor 15; fibroblast growth factor 15]
products gene name :
[Fgf15]
other gene names :
[Fgf15; Fgf15; FGF19; FGF-15]
uniprot entry name :
FGF15_MOUSE
specificity :
Recombinant and natural Mouse FGF-15
storage stability :
For long term storage, please store the entire kit at -20 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, Plasma, Tissue Homogenates, Cell Culture Supernates Or Other Biological Fluids.
products description :
Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids. Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
ncbi acc num :
NP_032029.1
ncbi gb acc num :
NM_008003.2
ncbi mol weight :
25,236 Da
ncbi pathways :
ARMS-mediated Activation Pathway (1324638); Adaptive Immune System Pathway (1323640); Axon Guidance Pathway (1323598); Cytokine Signaling In Immune System Pathway (1323763); DAP12 Interactions Pathway (1323743); DAP12 Signaling Pathway (1323744); Developmental Biology Pathway (1323597); Downstream Signal Transduction Pathway (1324645); Downstream Signaling Events Of B Cell Receptor (BCR) Pathway (1323654); Downstream Signaling Of Activated FGFR1 Pathway (1324563)
uniprot summary :
FGF19: Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. Belongs to the heparin-binding growth factors family. Protein type: Secreted, signal peptide; Secreted; Cell development/differentiation; Cytokine; Motility/polarity/chemotaxis. Cellular Component: extracellular region. Molecular Function: fibroblast growth factor receptor binding; growth factor activity; protein binding; receptor binding. Biological Process: fibroblast growth factor receptor signaling pathway; heart development; neural crest cell migration; positive regulation of cell proliferation; positive regulation of glucose import; positive regulation of JNK cascade; positive regulation of protein amino acid phosphorylation
size4 :
10x96-Strip-Wells