Mouse Coagulation factor XI ELISA Kit | MyBioSource MBS2881535 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Coagulation factor XI ELISA Kit

catalog :

MBS2881535

quantity :

48-Strip-Wells

price :

355 USD

product information

catalog number :

MBS2881535

products type :

ELISA Kit

products full name :

Mouse Coagulation factor XI ELISA Kit

products short name :

[Coagulation factor XI]

products name syn :

[Coagulation factor XI; FXI; Plasma thromboplastin antecedent; PTA; F11; 3.4.21.27]

other names :

[coagulation factor XI preproprotein; Coagulation factor XI; coagulation factor XI; coagulation factor XI; Plasma thromboplastin antecedent; PTA]

products gene name :

[F11]

other gene names :

[F11; F11; FXI; PTA; Cf11; AI503996; 1600027G01Rik; FXI; PTA]

uniprot entry name :

FA11_MOUSE

reactivity :

Mouse

sequence length :

624

specificity :

Recombinant and natural Mouse Wilms tumor protein homolog

storage stability :

For long term storage, please store the entire kit at -20 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Tissue Homogenates, Cell Culture Supernates Or Other Biological Fluids. Detection Range: 78-5000 pg/mL. Sensitivity: <39.6 pg/mL

other info2 :

Intra-assay Precision: Intra-Assay CV: <=4.6%. Inter-assay Precision: Inter-Assay CV: <=6.9%

products description :

Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids. Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.

ncbi gi num :

21312500

ncbi acc num :

NP_082342.1

ncbi gb acc num :

NM_028066.2

uniprot acc num :

Q91Y47

ncbi mol weight :

69,789 Da

ncbi pathways :

Blood Clotting Cascade Pathway (198388); Complement And Coagulation Cascades Pathway (198880); Complement And Coagulation Cascades Pathway (198335); Complement And Coagulation Cascades Pathway (83270); Complement And Coagulation Cascades Pathway (484); Formation Of Fibrin Clot (Clotting Cascade) Pathway (1323587); Hemostasis Pathway (1323559); Intrinsic Pathway Of Fibrin Clot Formation (1323589)

ncbi summary :

This gene encodes a glycoprotein coagulation factor that plays an important role in intrinsic pathway of blood coagulation and hemostasis. The encoded protein is an inactive zymogen that can be activated by coagulation factor XIIa, thrombin or factor XIa to generate active factor XIa protease. Mice lacking the encoded protein display a survival advantage during peritoneal sepsis and resist inflammation and bacterial accumulation upon infection with Listeria. [provided by RefSeq, Apr 2015]

uniprot summary :

F11: Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX. Defects in F11 are the cause of factor XI deficiency (FA11D); also known as plasma thromboplastin antecedent deficiency or Rosenthal syndrome. It is a hemorrhagic disease characterized by reduced levels and activity of factor XI resulting in moderate bleeding symptoms, usually occurring after trauma or surgery. Patients usually do not present spontaneous bleeding but women can present with menorrhagia. Hemorrhages are usually moderate. Belongs to the peptidase S1 family. Plasma kallikrein subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide; EC 3.4.21.27; Protease. Cellular Component: extracellular region; extracellular space. Molecular Function: heparin binding; hydrolase activity; peptidase activity; serine-type endopeptidase activity; serine-type peptidase activity. Biological Process: blood coagulation; hemostasis; plasminogen activation; positive regulation of fibrinolysis; proteolysis; regulation of blood coagulation

size1 :

48-Strip-Wells

price1 :

355 USD

size2 :

96-Strip-Wells

price2 :

475

size3 :

5x96-Strip-Wells

price3 :

2030

size4 :

10x96-Strip-Wells

price4 :

3700