catalog number :
MBS2881076
products type :
ELISA Kit
products full name :
Mouse Macrosialin ELISA Kit
products short name :
[Macrosialin]
products name syn :
[Macrosialin; Cd68; CD68]
other names :
[macrosialin; Macrosialin; macrosialin; CD68 antigen; CD_antigen: CD68]
products gene name :
[Cd68]
other gene names :
[Cd68; Cd68; Lamp4; gp110; Scard1]
uniprot entry name :
CD68_MOUSE
storage stability :
For long term storage, please store the entire kit at -20 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, Plasma, Tissue Homogenates, Cell Culture Supernates Or Other Biological Fluids.
products description :
Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids. Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
ncbi acc num :
NP_001277987.1
ncbi gb acc num :
NM_001291058.1
ncbi mol weight :
33,844 Da
ncbi pathways :
Lysosome Pathway (99272); Lysosome Pathway (96865); Macrophage Markers Pathway (672439)
uniprot summary :
CD68: Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. Belongs to the LAMP family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Cell surface. Cellular Component: endosome; integral to membrane; lysosome; membrane; plasma membrane
size4 :
10x96-Strip-Wells