catalog number :
MBS2880297
products type :
ELISA Kit
products full name :
Bovine Collagenase 3 ELISA Kit
products short name :
[Collagenase 3]
products name syn :
[Collagenase 3; Matrix metalloproteinase-13; MMP-13; MMP13]
other names :
[collagenase 3; Collagenase 3; collagenase 3; Matrix metalloproteinase-13; MMP-13]
products gene name :
[MMP13]
other gene names :
[MMP13; MMP13; MMP-13]
uniprot entry name :
MMP13_BOVIN
specificity :
Recombinant and natural Bovine Collagenase 3
storage stability :
For long term storage, please store the entire kit at -20 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: serum, plasma, tissue homogenates?cell culture supernates or other biological fluids. Detection Range: 0.312-20 ng/mL
other info2 :
Intra-assay Precision: Intra-Assay CV: ?5.5%. Inter-assay Precision: Inter-Assay CV: ?8.1%
products description :
Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates?cell culture supernates or other biological fluids.
ncbi acc num :
NP_776814.1
ncbi gb acc num :
NM_174389.2
ncbi mol weight :
53,921 Da
ncbi pathways :
Activation Of Matrix Metalloproteinases Pathway (1332689); Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway (1332678); Collagen Degradation Pathway (1332690); Collagen Formation Pathway (1332676); Degradation Of The Extracellular Matrix Pathway (1332688); Endochondral Ossification Pathway (920938); Extracellular Matrix Organization Pathway (1332675); Matrix Metalloproteinases Pathway (198565)
uniprot summary :
Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion ().
size4 :
10x96-Strip-Wells