product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Duck agouti-related protein (AGRP) ELISA Kit
catalog :
MBS283540
quantity :
48-Strip-Wells
price :
510 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS283540
products type :
ELISA Kit
products full name :
Duck agouti-related protein (AGRP) ELISA Kit
products short name :
agouti-related protein
other names :
agouti-related protein; Agouti-related protein; agouti-related protein; agouti related protein homolog; agouti related neuropeptide
products gene name :
AGRP
other gene names :
AGRP; AGRP; ART; AGRT; ASIP2; AGRT; ART
uniprot entry name :
AGRP_HUMAN
reactivity :
Duck
sequence length :
132
storage stability :
Store at 2-8 degree C.
ncbi gi num :
4501995
ncbi acc num :
NP_001129.1
ncbi gb acc num :
NM_001138.1
ncbi mol weight :
14,440 Da
ncbi pathways :
Adipocytokine Signaling Pathway (83093); Adipocytokine Signaling Pathway (505); Syndecan-3-mediated Signaling Events Pathway (137952)
ncbi summary :
This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. [provided by RefSeq, Dec 2009]
uniprot summary :
AGRP: Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R. Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner. Genetic variations in AGRP may be a cause of obesity (OBESITY). It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat. Protein type: Secreted; Hormone; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 16q22. Cellular Component: extracellular space; cell soma; Golgi lumen. Molecular Function: neuropeptide hormone activity; receptor binding. Biological Process: maternal process involved in pregnancy; hormone-mediated signaling; eating behavior; neuropeptide signaling pathway; photoperiodism; adult feeding behavior; feeding behavior; response to insulin stimulus. Disease: Obesity
size1 :
48-Strip-Wells
price1 :
510 USD
size2 :
96-Strip-Wells
price2 :
870
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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