catalog number :
MBS282151
products type :
ELISA Kit
products full name :
Human Plasminogen activator inhibitor 2 (SERPINB2) ELISA Kit
products short name :
[Plasminogen activator inhibitor 2]
other names :
[plasminogen activator inhibitor 2; Plasminogen activator inhibitor 2; plasminogen activator inhibitor 2; serpin family B member 2; Monocyte Arg-serpin; Placental plasminogen activator inhibitor; Serpin B2; Urokinase inhibitor]
products gene name :
[SERPINB2]
other gene names :
[SERPINB2; SERPINB2; PAI; PAI2; PAI-2; PLANH2; HsT1201; PAI2; PLANH2; PAI-2]
specificity :
This assay has high sensitivity and excellent specificity for detection of Human SERPINB2. No significant cross-reactivity or interference between Human SERPINB2 and analogues was observed.
storage stability :
Store at 2-8 degree C.
other info1 :
Samples: Serum, Plasma, Other biological fluids. Assay Type: Sandwich
other info2 :
Sample Volume: 1-200 uL. Precision: Intra-assay Precision (Precision within an assay). Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision. Inter-assay Precision (Precision between assays). Three samples of known concentration were tested in forty separate assays to assess inter-assay precision. CV (%) = SD/meanX100. Intra-Assay: CV. Inter-Assay: CV. Detection Wavelength: 450 nm
products description :
Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate SERPINB2 in samples. An antibody specific for SERPINB2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anySERPINB2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SERPINB2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SERPINB2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_001137290.1
ncbi gb acc num :
NM_001143818.1
ncbi mol weight :
46,596 Da
ncbi pathways :
Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Blood Clotting Cascade Pathway (198840); Dissolution Of Fibrin Clot Pathway (106061); Hemostasis Pathway (106028); Senescence And Autophagy Pathway (198780)
uniprot summary :
SERPINB2: Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell- derived PAI-1. Belongs to the serpin family. Ov-serpin subfamily. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 18q21.33-q22.1. Cellular Component: cytoplasm; extracellular region; extracellular space; plasma membrane. Molecular Function: serine-type endopeptidase inhibitor activity. Biological Process: fibrinolysis; negative regulation of apoptosis; wound healing
size4 :
10x96-Strip-Wells