catalog number :
MBS276435
products full name :
14-3-3 eta antibody [N1C3]
products short name :
14-3-3 eta
products name syn :
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein; eta polypeptide; YWHA1 antibody; YWHAH antibody; 14-3-3 protein eta antibody; 14-3-3 eta antibody; "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein; eta polypeptide antibody
other names :
14-3-3 protein gamma; 14-3-3 protein gamma; 14-3-3 protein gamma; 14-3-3 gamma; KCIP-1; protein kinase C inhibitor protein 1; protein phosphatase 1, regulatory subunit 170; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma; Protein kinase C inhibitor protein 1; KCIP-1
products gene name :
YWHAG
other gene names :
YWHAG; YWHAG; PPP1R170; 14-3-3GAMMA; KCIP-1
uniprot entry name :
1433G_HUMAN
reactivity :
Human. Predicted Reactivity: Rhesus Monkey (100%)
purity :
Purified by antigen-affinity chromatography.
storage stability :
Keep as concentrated solution. Aliquot and store at -20 degree C or below. Avoid multiple freeze-thaw cycles.
tested application :
Western Blot (WB)
app notes :
Western blot: 1:5000-1:20000. Optimal dilutions/concentrations should be determined by the researcher.
other info1 :
Storage Buffer: 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Predicted Target Size: 28 kDa. Positive Controls: NT2D1, IMR32, U87-MG, MCF-7
other info2 :
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 246 of 14-3-3 eta (Uniprot ID#Q04917). Antigen Species: Human. Research Area: Cancer; Type of cancer; Breast; Other; Stem Cell Development; Development; Morphogenesis
products description :
Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia. [provided by RefSeq]. Product Description: Rabbit Polyclonal antibody to 14-3-3 eta (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide)
ncbi gb acc num :
NM_012479
ncbi mol weight :
28,303 Da
ncbi pathways :
Activation Of BAD And Translocation To Mitochondria Pathway 105659!!Activation Of BH3-only Proteins Pathway 105658!!Anchoring Of The Basal Body To The Plasma Membrane Pathway 1127503!!Apoptosis Pathway 105648!!Assembly Of The Primary Cilium Pathway 1127502!!Calcium Regulation In The Cardiac Cell Pathway 198906!!Cell Cycle Pathway 530733!!Cell Cycle, Mitotic Pathway 105765!!Cell Cycle Pathway 198811!!Cell Cycle Pathway 83054
ncbi summary :
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008]