catalog number :
MBS275151
products full name :
14-3-3 beta antibody [N3C2], Internal
products short name :
14-3-3 beta
products name syn :
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein; beta polypeptide; GW128 antibody; HS1 antibody; KCIP-1 antibody; YWHAA antibody; YWHAB antibody; "brain protein 14-3-3; beta isoform antibody"; protein 1054 antibody; 14-3-3 protein beta/alpha antibody; protein kinase C inhibitor protein-1 antibody; "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein; alpha polypeptide antibody"; 14-3-3 alpha antibody; protein kinase C inhibitor protein 1 antibody; "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein; beta polypeptide antibody
other names :
14-3-3 protein beta/alpha; 14-3-3 protein beta/alpha; 14-3-3 protein beta/alpha; 14-3-3 alpha; brain protein 14-3-3, beta isoform; epididymis secretory protein Li 1; protein 1054; protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta; Protein 1054; Protein kinase C inhibitor protein 1; KCIP-1
products gene name :
YWHAB
other gene names :
YWHAB; YWHAB; HS1; GW128; YWHAA; KCIP-1; HEL-S-1; KCIP-1
uniprot entry name :
1433B_HUMAN
reactivity :
Human. Predicted Reactivity: Mouse (100%), Rat (100%), Chicken (93%), Rhesus Monkey (100%), Bovine (100%)
purity :
Affinity purified by Protein A.
concentration :
9.06 mg/ml
storage stability :
Keep as concentrated solution. Aliquot and store at -20 degree C or below. Avoid multiple freeze-thaw cycles.
tested application :
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
app notes :
ICC/IF: 1:100-1:1000. IHC (Formalin-fixed paraffin-embedded sections): 1:100-1:1000. Western blot: 1:500-1:3000. IHC (Formalin-fixed paraffin-embedded sections): suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0). Optimal dilutions/concentrations should be determined by the researcher.
other info1 :
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Predicted Target Size: 28 kDa. Positive Controls: 293T, H1299, HeLaS3, HepG2, Molt-4, Raji
other info2 :
Immunogen: Synthetic peptide corresponding to a region within amino acids 89 and 183 of 14-3-3 beta (Uniprot ID#P31946). Antigen Species: Human. Research Area: Cell Biology; Protein Trafficking; Zebrafish; Epigenetics
products description :
Background: This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq]. Product Description: Rabbit Polyclonal antibody to 14-3-3 beta (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide)
ncbi gb acc num :
NM_003404
ncbi mol weight :
27,850 Da
ncbi pathways :
ARMS-mediated Activation Pathway 106466!!Activation Of BAD And Translocation To Mitochondria Pathway 105659!!Activation Of BH3-only Proteins Pathway 105658!!Adaptive Immune System Pathway 366160!!Alpha6-Beta4 Integrin Signaling Pathway 198807!!Apoptosis Pathway 105648!!Axon Guidance Pathway 105688!!Butyrate Response Factor 1 (BRF1) Destabilizes MRNA Pathway 187213!!Calcium Regulation In The Cardiac Cell Pathway 198906!!Cell Cycle Pathway 198811
ncbi summary :
This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]