product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Rat Interleukin-18 binding prorein (IL-18BP) ELISA Kit
catalog :
MBS269372
quantity :
48-Strip-Wells
price :
290 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS269372
products type :
ELISA Kit
products full name :
Rat Interleukin-18 binding prorein (IL-18BP) ELISA Kit
products short name :
Interleukin-18 binding prorein (IL-18BP)
other names :
interleukin-18-binding protein isoform c; Interleukin-18-binding protein; interleukin-18-binding protein; IL-18BP; tadekinig-alfa; MC51L-53L-54L homolog gene product; interleukin 18 binding protein; Tadekinig-alfa
products gene name :
IL-18BP
other gene names :
IL18BP; IL18BP; IL18BPa; IL-18BP
uniprot entry name :
I18BP_HUMAN
reactivity :
Rat
sequence length :
199
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Samples: Rat serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant IL-18BP concentration. Assay Type: Sandwich. Detection Range: 10 ng/ml-0.156 ng/ml
products description :
Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Rat IL-18BP monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
ncbi gi num :
323098348
ncbi acc num :
NP_005690.2
ncbi gb acc num :
NM_005699.3
ncbi mol weight :
17,478 Da
ncbi summary :
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
uniprot summary :
IL18BP: Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 11q13. Cellular Component: extracellular space; extracellular region. Molecular Function: receptor antagonist activity; interleukin-18 binding. Biological Process: T-helper 1 type immune response; response to lipopolysaccharide
size1 :
48-Strip-Wells
price1 :
290 USD
size2 :
96-Strip-Wells
price2 :
450
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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