catalog number :
MBS269194
products type :
ELISA Kit
products full name :
Guinea pig Tissue Inhibitors Of Metalloproteinase 1 (TIMP-1) ELISA Kit
products short name :
Tissue Inhibitors Of Metalloproteinase 1 (TIMP-1)
other names :
tissue inhibitor of metalloproteinase 1, partial; Metalloproteinase inhibitor 1; metalloproteinase inhibitor 1; TIMP-1; collagenase inhibitor; erythroid potentiating activity; erythroid-potentiating activity; fibroblast collagenase inhibitor; tissue inhibitor of metalloproteinases 1; TIMP metallopeptidase inhibitor 1; Erythroid-potentiating activity; EPA; Fibroblast collagenase inhibitor; Collagenase inhibitor; Tissue inhibitor of metalloproteinases 1; TIMP-1
products gene name :
TIMP-1
other gene names :
TIMP1; TIMP1; EPA; EPO; HCI; CLGI; TIMP; CLGI; TIMP; EPA; Collagenase inhibitor; TIMP-1
uniprot entry name :
TIMP1_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
ncbi acc num :
AAA75558.1
ncbi mol weight :
23,171 Da
ncbi pathways :
Activation Of Matrix Metalloproteinases Pathway 576264!!Degradation Of The Extracellular Matrix Pathway 576263!!Extracellular Matrix Organization Pathway 576262!!HIF-1 Signaling Pathway 695200!!Hemostasis Pathway 106028!!IL6-mediated Signaling Events Pathway 137932!!Matrix Metalloproteinases Pathway 198900!!Platelet Activation, Signaling And Aggregation Pathway 106034!!Platelet Degranulation Pathway 106050!!Response To Elevated Platelet Cytosolic Ca2+ Pathway 106048
ncbi summary :
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]