Mouse Dopamine Receptor D1 (DRD1) ELISA Kit | MyBioSource MBS269095 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Dopamine Receptor D1 (DRD1) ELISA Kit

catalog :

MBS269095

quantity :

48-Strip-Wells

price :

290 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS269095

products type :

ELISA Kit

products full name :

Mouse Dopamine Receptor D1 (DRD1) ELISA Kit

products short name :

Dopamine Receptor D1 (DRD1)

other names :

dopamine receptor D1; D(1A) dopamine receptor; D(1A) dopamine receptor; D(1A) dopamine receptor; dopamine D1 receptor; dopamine receptor D1; Dopamine D1 receptor

products gene name :

DRD1

other gene names :

DRD1; DRD1; DADR; DRD1A

uniprot entry name :

DRD1_HUMAN

reactivity :

Mouse

sequence length :

446

specificity :

No cross-reaction with other factors.

storage stability :

Store all reagents at 2-8 degree C.

other info1 :

Samples: Mouse serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant DRD1 concentration. Assay Type: Sandwich. Detection Range: 10 ng/ml-0.156 ng/ml. Sensitivity: 0.05 ng/ml.

other info2 :

Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%

products description :

. Principle of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Mouse DRD1 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

ncbi gi num :

20269979

ncbi acc num :

AAM18131.1

ncbi mol weight :

49,293 Da

ncbi pathways :

Alcoholism Pathway (585563); Alcoholism Pathway (587116); Amine Ligand-binding Receptors Pathway (106363); Amphetamine Addiction Pathway (547607); Amphetamine Addiction Pathway (550546); Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Cocaine Addiction Pathway (546258); Cocaine Addiction Pathway (546273)

ncbi summary :

This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

DRD1: a G-protein coupled receptor.One of the five types (D1 to D5) of receptors for dopamine. The most abundant dopamine receptor in the central nervous system. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Interacts with calcyon. Protein type: Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 5q35.1. Cellular Component: endoplasmic reticulum membrane; integral to plasma membrane; plasma membrane; nucleus. Molecular Function: protein binding; dopamine receptor activity; dopamine binding; dopamine D1 receptor-like receptor activity. Biological Process: synaptic transmission, dopaminergic; peristalsis; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); behavioral fear response; prepulse inhibition; positive regulation of potassium ion transport; generation of action potential; thermoregulation; adult walking behavior; G-protein signaling, adenylate cyclase activating pathway; dopamine metabolic process; vasodilation; positive regulation of synaptic transmission, glutamatergic; synaptogenesis; behavioral response to cocaine; protein import into nucleus; conditioned taste aversion; positive regulation of cAMP biosynthetic process; visual learning; dopamine receptor, adenylate cyclase activating pathway; response to drug; grooming behavior; dopamine transport; dentate gyrus development; cerebral cortex GABAergic interneuron migration; striatum development; maternal behavior; adenylate cyclase activation; response to amphetamine; regulation of dopamine metabolic process; regulation of dopamine uptake; mating behavior; transmission of nerve impulse; astrocyte development; memory; G-protein signaling, coupled to cyclic nucleotide second messenger; habituation; glucose import; operant conditioning; sensitization; dopamine receptor, phospholipase C activating pathway; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of cell migration

size1 :

48-Strip-Wells

price1 :

290 USD

size2 :

96-Strip-Wells

price2 :

450

more info or order :

MyBioSource product webpage