product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Caldesmon (CALD) ELISA Kit
catalog :
MBS269006
quantity :
48-Strip-Wells
price :
275 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS269006
products type :
ELISA Kit
products full name :
Human Caldesmon (CALD) ELISA Kit
products short name :
Caldesmon (CALD)
other names :
caldesmon; Caldesmon; caldesmon; caldesmon 1
products gene name :
CALD
other gene names :
CALD1; CALD1; CDM; HCAD; LCAD; H-CAD; L-CAD; NAG22; CAD; CDM; CDM
uniprot entry name :
CALD1_HUMAN
reactivity :
Human
sequence length :
793
storage stability :
Store all reagents at 2-8 degree C.
ncbi gi num :
180195
ncbi acc num :
AAA58419.1
ncbi mol weight :
65,620 Da
ncbi pathways :
Muscle Contraction Pathway (106261); Myometrial Relaxation And Contraction Pathways (198759); Smooth Muscle Contraction Pathway (161025); Vascular Smooth Muscle Contraction Pathway (96530); Vascular Smooth Muscle Contraction Pathway (96866)
ncbi summary :
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
uniprot summary :
Caldesmon: a cytoskeletal protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells. May act as a bridge between myosin and actin filaments. Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also plays an essential role during cellular mitosis and receptor capping. Five alternatively spliced isoforms have been described. Protein type: Actin-binding. Chromosomal Location of Human Ortholog: 7q33. Cellular Component: cytoskeleton; myofibril; plasma membrane; cytosol; actin cap; actin cytoskeleton. Molecular Function: calmodulin binding; myosin binding; actin binding; tropomyosin binding. Biological Process: muscle contraction; cell motility
size1 :
48-Strip-Wells
price1 :
275 USD
size2 :
96-Strip-Wells
price2 :
420
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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