catalog number :
MBS268301
products type :
ELISA Kit
products full name :
Rat C-Type Natriuretic Peptide (CNP) ELISA Kit
products short name :
C-Type Natriuretic Peptide (CNP)
other names :
C-type natriuretic peptide; C-type natriuretic peptide; C-type natriuretic peptide; natriuretic peptide precursor C; natriuretic peptide C
other gene names :
NPPC; NPPC; CNP; CNP2; CNP2
uniprot entry name :
ANFC_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Samples: Rat serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant CNP concentration. Detection Range: 2000 pg/ml-31.2 pg/ml. Sensitivity: 12 pg/ml.
other info2 :
Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%
ncbi acc num :
NP_077720.1
ncbi gb acc num :
NM_024409.2
ncbi mol weight :
13,246 Da
ncbi summary :
The protein encoded by this gene is proteolytically processed to form a secreted hormone of the natriuretic peptide family. The encoded hormone regulates the growth and differentiation of cartilaginous growth plate chondrocytes and may also be vasoactive and natriuretic. [provided by RefSeq, Sep 2011]
uniprot summary :
NPPC: Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3. Belongs to the natriuretic peptide family. Protein type: Secreted, signal peptide; Secreted; Hormone. Chromosomal Location of Human Ortholog: 2q37.1. Cellular Component: extracellular space; secretory granule. Molecular Function: protein homodimerization activity; peptide hormone receptor binding; hormone activity; receptor binding. Biological Process: response to drug; cGMP biosynthetic process; ossification; regulation of smooth muscle cell proliferation; regulation of cAMP metabolic process; regulation of multicellular organism growth; negative regulation of meiotic cell cycle; positive regulation of vasodilation; negative regulation of DNA metabolic process; post-embryonic development; positive regulation of osteoblast differentiation; negative regulation of cell proliferation; response to ethanol; positive regulation of cGMP biosynthetic process; receptor guanylyl cyclase signaling pathway; response to hypoxia; regulation of cGMP metabolic process; regulation of blood vessel size