Chicken Inhibin A (INHA) ELISA Kit | MyBioSource MBS266765 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Chicken Inhibin A (INHA) ELISA Kit

catalog :

MBS266765

quantity :

48-Strip-Wells

price :

315 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS266765

products type :

ELISA Kit

products full name :

Chicken Inhibin A (INHA) ELISA Kit

products short name :

Inhibin A (INHA)

other names :

inhibin beta B chain preproprotein; Inhibin beta B chain; inhibin beta B chain; Inhibin, beta-2; activin beta-B chain; activin AB beta polypeptide; inhibin, beta B; Activin beta-B chain

products gene name :

INHA

other gene names :

INHBB; INHBB

uniprot entry name :

INHBB_HUMAN

reactivity :

Chicken

sequence length :

407

specificity :

No cross-reaction with other factors.

storage stability :

Store all reagents at 2-8 degree C.

other info1 :

Samples: Chicken serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant INHA concentration. Assay Type: Sandwich. Detection Range: 1000 pg/ml-15.6 pg/ml. Sensitivity: the minimum detectable Chicken INHA up to 5 pg/ml.

other info2 :

Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%

products description :

Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Chicken INHA monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

ncbi gi num :

154813204

ncbi acc num :

NP_002184.2

ncbi gb acc num :

NM_002193.2

ncbi mol weight :

45,122 Da

ncbi pathways :

AGE/RAGE Pathway (698754); Antagonism Of Activin By Follistatin Pathway (730350); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Glycoprotein Hormones Pathway (160989); Metabolism Of Proteins Pathway (106230); Peptide Hormone Biosynthesis Pathway (160988); Peptide Hormone Metabolism Pathway (771603); Signal Transduction Pathway (477114); Signaling By Activin Pathway (730349)

ncbi summary :

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq, Jul 2008]

uniprot summary :

INHBB: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. Belongs to the TGF-beta family. Protein type: Cell development/differentiation; Secreted; Secreted, signal peptide; Cytokine. Chromosomal Location of Human Ortholog: 2cen-q13. Cellular Component: extracellular space; perinuclear region of cytoplasm; extracellular region. Molecular Function: protein binding; protein homodimerization activity; growth factor activity; hormone activity; cytokine activity; transforming growth factor beta receptor binding; host cell surface receptor binding. Biological Process: fat cell differentiation; activin receptor signaling pathway; defense response; negative regulation of hepatocyte growth factor biosynthetic process; cellular response to starvation; negative regulation of follicle-stimulating hormone secretion; negative regulation of insulin secretion; regulation of apoptosis; ovarian follicle development; cellular response to insulin stimulus; response to mechanical stimulus; regulation of MAPKKK cascade; positive regulation of follicle-stimulating hormone secretion; cell differentiation; cell development; oocyte development; growth

size1 :

48-Strip-Wells

price1 :

315 USD

size2 :

96-Strip-Wells

price2 :

490

more info or order :

MyBioSource product webpage