catalog number :
MBS265844
products type :
ELISA Kit
products full name :
Human Anti-Smooth Muscle Antibody (ASMA) ELISA Kit
products short name :
Anti-Smooth Muscle Antibody (ASMA)
other names :
actin-related protein 2/3 complex subunit 3 isoform 2; Actin-related protein 2/3 complex subunit 3; actin-related protein 2/3 complex subunit 3; arp2/3 complex 21 kDa subunit; ARP2/3 protein complex subunit p21; actin related protein 2/3 complex, subunit 3, 21kDa; Arp2/3 complex 21 kDa subunit; p21-ARC
products gene name :
ASMA
other gene names :
ARPC3; ARPC3; ARC21; p21-Arc; ARC21; p21-ARC
uniprot entry name :
ARPC3_HUMAN
specificity :
No cross-reaction with other factors.
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Samples: Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant ASMA concentration. Assay Type: Sandwich. Detection Range: 100 ng/ml-1.56 ng/ml. Sensitivity: 0.5 ng/ml.
other info2 :
Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%
products description :
Principle of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human ASMA monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
ncbi acc num :
NP_001274151.1
ncbi gb acc num :
NM_001287222.1
ncbi mol weight :
20,547 Da
ncbi pathways :
Axon Guidance Pathway (105688); B Cell Receptor Signaling Pathway (198909); Bacterial Invasion Of Epithelial Cells Pathway (149807); Bacterial Invasion Of Epithelial Cells Pathway (148661); CDC42 Signaling Events Pathway (137994); Developmental Biology Pathway (477129); EPH-Ephrin Signaling Pathway (1016174); EPHB-mediated Forward Signaling Pathway (1016176); ErbB1 Downstream Signaling Pathway (138057); Fc Gamma R-mediated Phagocytosis Pathway (114228)
ncbi summary :
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been conserved through evolution and is implicated in the control of actin polymerization in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]
uniprot summary :
ARPC3: one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. Protein type: Cytoskeletal; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 12q24.11. Cellular Component: Arp2/3 protein complex; focal adhesion; membrane; lamellipodium; cytosol; actin cytoskeleton. Molecular Function: actin filament binding; protein binding; structural constituent of cytoskeleton. Biological Process: axon guidance; ephrin receptor signaling pathway; innate immune response; cell motility