catalog number :
MBS265165
products type :
ELISA Kit
products full name :
Chicken Pregnancy Specificbeta1Glycoprotein (SP1 / PSbeta1-G) ELISA Kit
products short name :
Pregnancy Specificbeta1Glycoprotein (SP1 / PSbeta1-G)
products name syn :
Chicken Pregnancy Specificb1Glycoprotein (SP1 / PSb1-G) ELISA Kit
other names :
pregnancy zone protein; Pregnancy zone protein; pregnancy zone protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6; pregnancy-zone protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6
products gene name :
SP1 / PSbeta1-G
other gene names :
PZP; PZP; CPAMD6; CPAMD6
uniprot entry name :
PZP_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
ncbi acc num :
NP_002855.2
ncbi gb acc num :
NM_002864.2
ncbi mol weight :
140,368 Da
uniprot summary :
PZP: Is able to inhibit all four classes of proteinases by a unique trapping mechanism. This protein has a peptide stretch, called the bait region which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase. Belongs to the protease inhibitor I39 (alpha-2- macroglobulin) family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 12p13-p12.2. Cellular Component: extracellular region. Molecular Function: serine-type endopeptidase inhibitor activity; endopeptidase inhibitor activity. Biological Process: female pregnancy