catalog number :
MBS264841
products type :
ELISA Kit
products full name :
Guinea pig Interferon Beta (IFN-beta) ELISA Kit
products short name :
Interferon Beta (IFN-beta)
products name syn :
Guinea pig Interferon Beta (IFN-b) ELISA Kit
other names :
interferon beta; Interferon beta; interferon beta; IFN-beta; fibroblast interferon; interferon, beta 1, fibroblast; Fibroblast interferon
products gene name :
IFN-beta
other gene names :
IFNB1; IFNB1; IFB; IFF; IFNB; IFB; IFNB; IFN-beta
uniprot entry name :
IFNB_HUMAN
specificity :
No cross-reaction with other factors.
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Samples: Guinea pig serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant IFN-? concentration. Assay Type: Sandwich. Detection Range: 1000 pg/ml-315.6 pg/ml. Sensitivity: 5 pg/ml.
other info2 :
Intra-assay Precision: ? 8%. Inter-assay Precision: ? 12%
products description :
Princple of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Guinea pig IFN-? monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
ncbi acc num :
NP_002167.1
ncbi gb acc num :
NM_002176.2
ncbi mol weight :
22,294 Da
ncbi pathways :
Chagas Disease (American Trypanosomiasis) Pathway (147809); Chagas Disease (American Trypanosomiasis) Pathway (147795); Cytokine Signaling In Immune System Pathway (366171); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Cytokines And Inflammatory Response Pathway (198794); Cytosolic DNA-sensing Pathway (125137); Cytosolic DNA-sensing Pathway (124833); EBV LMP1 Signaling Pathway (198790); Factors Involved In Megakaryocyte Development And Platelet Production Pathway (187196)
uniprot summary :
IFNB1: Has antiviral, antibacterial and anticancer activities. Belongs to the alpha/beta interferon family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 9p21. Cellular Component: extracellular space; extracellular region. Molecular Function: interferon-alpha/beta receptor binding; cytokine activity. Biological Process: B cell proliferation; adaptive immune response; response to virus; cytokine and chemokine mediated signaling pathway; regulation of MHC class I biosynthetic process; natural killer cell activation; negative regulation of T cell differentiation; humoral immune response; T cell activation during immune response; response to exogenous dsRNA; cell surface receptor linked signal transduction; negative regulation of viral genome replication; B cell differentiation; defense response to bacterium; positive regulation of innate immune response; natural killer cell activation during immune response; innate immune response; positive regulation of transcription from RNA polymerase II promoter; blood coagulation; defense response to virus; positive regulation of peptidyl-serine phosphorylation of STAT protein; B cell activation during immune response