product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Deoxyribonuclease I (DNASE1) ELISA Kit
catalog :
MBS264434
quantity :
48-Strip-Wells
price :
250 USD
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS264434 image 1
product information
catalog number :
MBS264434
products type :
ELISA Kit
products full name :
Human Deoxyribonuclease I (DNASE1) ELISA Kit
products short name :
[Deoxyribonuclease I (DNASE1)]
other names :
[deoxyribonuclease I; Deoxyribonuclease-1; Deoxyribonuclease I; DNase I; INN: Dornase alfa]
products gene name :
[DNASE1]
other gene names :
[DNASE1; DNL1; DRNI; DNase I]
uniprot entry name :
DNAS1_HUMAN
reactivity :
Human
sequence length :
282
specificity :
No cross-reaction with other factors.
storage stability :
Store all reagents at 2-8 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Human Serum, Plasma Or Cell Culture Supernatant And Organizations In The Natural And Recombinant D-La Concentration. Assay Type: Sandwich. Detection Range: 100 mmol/L-1.56 mmol/L. Sensitivity: 0.5 mmol/L.
other info2 :
Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%
products description :
Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human D-LA monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
ncbi gi num :
1197173
ncbi acc num :
BAA11841.1
ncbi mol weight :
31,434 Da
uniprot summary :
DNASE1: Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization. Defects in DNASE1 are a cause of susceptibility to systemic lupus erythematosus (SLE). A chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system. Belongs to the DNase I family. Protein type: EC 3.1.21.1; Deoxyribonuclease; Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: extracellular region; nuclear envelope; nucleus. Molecular Function: protein binding; deoxyribonuclease I activity; actin binding; endodeoxyribonuclease activity. Biological Process: apoptosis; DNA catabolic process, endonucleolytic. Disease: Systemic Lupus Erythematosus
size1 :
48-Strip-Wells
price1 :
250 USD
size2 :
96-Strip-Wells
price2 :
365
size3 :
5x96-Strip-Wells
price3 :
1480
size4 :
10x96-Strip-Wells
price4 :
2620
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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