ELISA/assay

Mouse A Disintegrin And Metalloprotease 8 (ADAM8) ELISA Kit

MBS264057

48-Strip-Wells

290 USD

ELISA Kit

Mouse A Disintegrin And Metalloprotease 8 (ADAM8) ELISA Kit

A Disintegrin And Metalloprotease 8 (ADAM8)

A disintegrin and metalloproteinase with thrombospondin motifs 8 preproprotein; A disintegrin and metalloproteinase with thrombospondin motifs 8; A disintegrin and metalloproteinase with thrombospondin motifs 8; METH-2; METH-8; ADAMTS-8; ADAM-TS 8; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8; ADAM metallopeptidase with thrombospondin type 1 motif, 8; METH-2; METH-8

ADAM8

ADAMTS8; ADAMTS8; METH2; ADAM-TS8; METH2; ADAM-TS 8; ADAM-TS8; ADAMTS-8

ATS8_HUMAN

Mouse

889

No cross-reaction with other factors.

Store all reagents at 2-8 degree C.

Samples: Mouse serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant ADAM8 concentration. Assay Type: Sandwich. Detection Range: 1000 pg/ml-15.6pg/ml. Sensitivity: 5 pg/ml.

Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%

Principle of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Mouse ADAM8 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

153792351

NP_008968.4

NM_007037.4

96,460 Da

Degradation Of The Extracellular Matrix Pathway (576263); Extracellular Matrix Organization Pathway (576262); Metabolism Of Proteins Pathway (106230); O-glycosylation Of TSR Domain-containing Proteins Pathway (980460); O-linked Glycosylation Pathway (980459); Post-translational Protein Modification Pathway (161012)

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. [provided by RefSeq, Jul 2008]

ADAMTS8: Has anti-angiogenic properties. Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; EC 3.4.24.-; Cell cycle regulation; Secreted; Protease. Chromosomal Location of Human Ortholog: 11q25. Cellular Component: extracellular matrix; proteinaceous extracellular matrix. Molecular Function: integrin binding; heparin binding; zinc ion binding; metallopeptidase activity; metalloendopeptidase activity; low affinity phosphate transmembrane transporter activity. Biological Process: negative regulation of cell proliferation; proteolysis

48-Strip-Wells

290 USD

96-Strip-Wells

450