Human hyaluronidase (HAase) ELISA Kit | MyBioSource MBS263963 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human hyaluronidase (HAase) ELISA Kit

catalog :

MBS263963

quantity :

48-Strip-Wells

price :

275 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS263963

products type :

ELISA Kit

products full name :

Human hyaluronidase (HAase) ELISA Kit

products short name :

hyaluronidase (HAase)

other names :

hyaluronidase; Hyaluronidase-3; hyaluronidase-3; lung carcinoma protein 3; hyaluronoglucosaminidase 3; Hyaluronoglucosaminidase-3; Lung carcinoma protein 3; LuCa-3

products gene name :

HAase

other gene names :

HYAL3; HYAL3; LUCA3; HYAL-3; LUCA-3; LUCA3; Hyal-3; LuCa-3

uniprot entry name :

HYAL3_HUMAN

reactivity :

Human

sequence length :

463

storage stability :

Store all reagents at 2-8 degree C.

other info1 :

Samples: Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant HAase concentration. Assay Type: Sandwich. Detection Range: 200 ng/ml-3.12 ng/ml. Sensitivity: 0.6 ng/ml.

other info2 :

Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%

products description :

Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human HAase monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

ncbi gi num :

2935328

ncbi acc num :

AAC70915.1

ncbi mol weight :

15,865 Da

ncbi pathways :

Chondroitin Sulfate Degradation Pathway (413376); Chondroitin Sulfate Degradation Pathway (468247); Dermatan Sulfate Degradation Pathway (413375); Dermatan Sulfate Degradation Pathway (468240); Glycosaminoglycan Degradation Pathway (82981); Glycosaminoglycan Degradation Pathway (355)

ncbi summary :

This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]

uniprot summary :

HYAL3: a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]. Protein type: Hydrolase; EC 3.2.1.35; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 3p21.3. Cellular Component: lysosome; extracellular region; cytoplasmic vesicle. Molecular Function: viral receptor activity; hyaluronoglucuronidase activity; hyalurononglucosaminidase activity. Biological Process: response to antibiotic; response to virus; cartilage development; carbohydrate metabolic process; inflammatory response; hyaluronan catabolic process

size1 :

48-Strip-Wells

price1 :

275 USD

size2 :

96-Strip-Wells

price2 :

420

more info or order :

MyBioSource product webpage