catalog number :
MBS263435
products type :
ELISA Kit
products full name :
Goat Bone Morphogenetic Protein 2 (BMP-2) ELISA Kit
products short name :
[Bone Morphogenetic Protein 2 (BMP-2)]
other names :
[bone morphogenetic protein 2 preproprotein; Bone morphogenetic protein 2; bone morphogenetic protein 2; BMP-2A; bone morphogenetic protein 2A; bone morphogenetic protein 2; Bone morphogenetic protein 2A; BMP-2A]
products gene name :
[BMP-2]
other gene names :
[BMP2; BMP2; BDA2; BMP2A; BMP2A; BMP-2; BMP-2A]
uniprot entry name :
BMP2_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
ncbi acc num :
NP_001191.1
ncbi gb acc num :
NM_001200.2
ncbi mol weight :
44,702 Da
ncbi pathways :
Adipogenesis Pathway (198832); BDNF Signaling Pathway (712093); BMP Signalling And Regulation Pathway (198910); Basal Cell Carcinoma Pathway (83113); Basal Cell Carcinoma Pathway (525); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Elastic Fibre Formation Pathway (730310); Extracellular Matrix Organization Pathway (576262); Heart Development Pathway (198802)
ncbi summary :
The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation. [provided by RefSeq, Jul 2008]
uniprot summary :
Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451).
size4 :
10x96-Strip-Wells