catalog number :
MBS262984
products type :
ELISA Kit
products full name :
Goat 14-3-3 Protein (14-3-3 Pro) ELISA Kit
products short name :
14-3-3 Protein (14-3-3 Pro)
other names :
14-3-3 protein; 14-3-3 protein eta; 14-3-3 protein eta; 14-3-3 eta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta; Protein AS1
products gene name :
14-3-3 Pro
other gene names :
YWHAH; YWHAH; YWHA1; YWHA1
uniprot entry name :
1433F_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
ncbi acc num :
CAA56676.1
ncbi mol weight :
28,219 Da
ncbi pathways :
Activation Of BAD And Translocation To Mitochondria Pathway (105659); Activation Of BH3-only Proteins Pathway (105658); Alpha6-Beta4 Integrin Signaling Pathway (198807); Apoptosis Pathway (105648); Calcium Regulation In The Cardiac Cell Pathway (198906); Cell Cycle Pathway (198811); Cell Cycle Pathway (83054); Cell Cycle Pathway (463); Class I PI3K Signaling Events Mediated By Akt Pathway (138020); Epstein-Barr Virus Infection Pathway (585562)
ncbi summary :
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009]
uniprot summary :
14-3-3 eta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Protein type: Adaptor/scaffold; Nuclear receptor co-regulator. Chromosomal Location of Human Ortholog: 22q12.3. Cellular Component: cytoplasmic vesicle membrane; cytoplasm; plasma membrane; cytosol. Molecular Function: protein domain specific binding; insulin-like growth factor receptor binding; protein binding; enzyme binding; sodium channel regulator activity; protein heterodimerization activity; actin binding; glucocorticoid receptor binding. Biological Process: intracellular protein transport; substantia nigra development; regulation of neuron differentiation; apoptosis; positive regulation of transcription, DNA-dependent; glucocorticoid receptor signaling pathway; regulation of synaptic plasticity; glucocorticoid catabolic process; negative regulation of dendrite morphogenesis; regulation of sodium ion transport