ELISA/assay

Porcine Insulin Like Growth Factor Binding Protein 1 (IGFBP-1) ELISA Kit

MBS262893

48-Strip-Wells

315 USD

ELISA Kit

Porcine Insulin Like Growth Factor Binding Protein 1 (IGFBP-1) ELISA Kit

Insulin Like Growth Factor Binding Protein 1 (IGFBP-1)

insulin-like growth factor-binding protein 1; Insulin-like growth factor-binding protein 1; insulin-like growth factor-binding protein 1; IBP-1; IGFBP-1; binding protein-25; binding protein-26; binding protein-28; placental protein 12; IGF-binding protein 1; amniotic fluid binding protein; growth hormone independent-binding protein; alpha-pregnancy-associated endometrial globulin; insulin-like growth factor binding protein 1; Placental protein 12; PP12

IGFBP-1

IGFBP1; IGFBP1; AFBP; IBP1; PP12; IGF-BP25; hIGFBP-1; IBP1; IBP-1; IGF-binding protein 1; IGFBP-1; PP12

IBP1_HUMAN

Porcine

259

No cross-reaction with other factors.

Store all reagents at 2-8 degree C.

Samples: Porcine serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant IGFBP-1 concentration. Assay Type: Sandwich. Detection Range: 10 ng/ml-0.156 ng/ml. Sensitivity: 0.05 ng/ml.

Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%

Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Porcine IGFBP-1 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

4504615

NP_000587.1

NM_000596.2

27,904 Da

Activation Of Genes By ATF4 Pathway (530772); AhR Pathway (755436); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); HIF-1-alpha Transcription Factor Network Pathway (138045); Metabolism Of Proteins Pathway (106230); Myometrial Relaxation And Contraction Pathways (198759); PERK Regulated Gene Expression Pathway (105907); Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway (105908); Unfolded Protein Response Pathway (105904)

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008]

IGFBP1: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 7p12.3. Cellular Component: extracellular space; extracellular region. Molecular Function: insulin-like growth factor binding; insulin-like growth factor I binding; insulin-like growth factor II binding. Biological Process: unfolded protein response, activation of signaling protein activity; regulation of insulin-like growth factor receptor signaling pathway; cellular protein metabolic process; tissue regeneration; unfolded protein response; insulin receptor signaling pathway; signal transduction; positive regulation of cell growth

48-Strip-Wells

315 USD

96-Strip-Wells

490