catalog number :
MBS262748
products type :
ELISA Kit
products full name :
Goat A Disintegrin And Metalloprotease 8 (ADAM8) ELISA Kit
products short name :
A Disintegrin And Metalloprotease 8 (ADAM8)
other names :
A disintegrin and metalloproteinase with thrombospondin motifs 8 preproprotein; A disintegrin and metalloproteinase with thrombospondin motifs 8; A disintegrin and metalloproteinase with thrombospondin motifs 8; METH-2; METH-8; ADAMTS-8; ADAM-TS 8; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8; ADAM metallopeptidase with thrombospondin type 1 motif, 8; METH-2; METH-8
products gene name :
ADAM8
other gene names :
ADAMTS8; ADAMTS8; METH2; ADAM-TS8; METH2; ADAM-TS 8; ADAM-TS8; ADAMTS-8
uniprot entry name :
ATS8_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
ncbi acc num :
NP_008968.4
ncbi gb acc num :
NM_007037.4
ncbi mol weight :
96,460 Da
ncbi pathways :
Degradation Of The Extracellular Matrix Pathway 576263!!Extracellular Matrix Organization Pathway 576262!!Metabolism Of Proteins Pathway 106230!!O-glycosylation Of TSR Domain-containing Proteins Pathway 980460!!O-linked Glycosylation Pathway 980459!!Post-translational Protein Modification Pathway 161012
ncbi summary :
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. [provided by RefSeq, Jul 2008]