Bovine 5-Hydroxytryptamine receptor 2A(5HTR 2A) ELISA Kit | MyBioSource MBS2610462 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Bovine 5-Hydroxytryptamine receptor 2A(5HTR 2A) ELISA Kit

catalog :

MBS2610462

quantity :

48-Strip-Wells

price :

275 USD

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS2610462

products type :

ELISA Kit

products full name :

Bovine 5-Hydroxytryptamine receptor 2A(5HTR 2A) ELISA Kit

products short name :

[5-Hydroxytryptamine receptor 2A (5HTR 2A)]

other names :

[5-hydroxytryptamine receptor 2A; 5-hydroxytryptamine receptor 2A; 5-hydroxytryptamine receptor 2A; 5-hydroxytryptamine receptor 2A; Serotonin receptor 2A]

products gene name :

[5HTR 2A]

other gene names :

[HTR2A; HTR2A; HTR2; 5-HT2A; HTR2; 5-HT-2; 5-HT-2A]

uniprot entry name :

5HT2A_HUMAN

reactivity :

Bovine

sequence length :

471

specificity :

No cross-reaction with other factors.

storage stability :

Store all reagents at 2-8 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Bovine Serum, Plasma Or Cell Culture Supernatant And Organizations In The Natural And Recombinant 17beta-Estradiol Concentration. Assay Type: Sandwich. Detection Range: 20 ng/ml-0.312 ng/ml. Sensitivity: 0.06 ng/ml.

other info2 :

Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%

products description :

Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Bovine 17beta-Estradiol monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

ncbi gi num :

20379138

ncbi mol weight :

43,940 Da

ncbi pathways :

Amine Ligand-binding Receptors Pathway (1269553); Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); G Alpha (q) Signalling Events Pathway (1269578); GPCR Downstream Signaling Pathway (1269574); GPCR Ligand Binding Pathway (1269544); GPCRs, Class A Rhodopsin-like Pathway (198886); GPCRs, Other Pathway (198765); Gap Junction Pathway (83072)

ncbi summary :

This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

uniprot summary :

5-HT(2A): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production. Belongs to the G-protein coupled receptor 1 family. Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR. Chromosomal Location of Human Ortholog: 13q14-q21. Cellular Component: dendrite; plasma membrane. Molecular Function: drug binding; neurotransmitter receptor activity; serotonin binding; serotonin receptor activity. Biological Process: cellular calcium ion homeostasis; G-protein signaling, adenylate cyclase inhibiting pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); phosphoinositide 3-kinase cascade; phospholipase C activation; positive regulation of phosphatidylinositol biosynthetic process; release of sequestered calcium ion into cytosol; response to drug; serotonin receptor signaling pathway; synaptic transmission. Disease: Alcohol Dependence; Anorexia Nervosa, Susceptibility To, 1; Major Depressive Disorder; Obsessive-compulsive Disorder; Schizophrenia

size1 :

48-Strip-Wells

price1 :

275 USD

size2 :

96-Strip-Wells

price2 :

435

size3 :

5x96-Strip-Wells

price3 :

1755

size4 :

10x96-Strip-Wells

price4 :

3150

more info or order :

MyBioSource product webpage