ELISA/assay

Canine ADAM metallopeptidase with ombospondin type 1 motif, 13 (ADAMTS13) ELISA Kit

MBS2605062

48-Strip-Wells

275 USD

ELISA Kit

Canine ADAM metallopeptidase with ombospondin type 1 motif, 13 (ADAMTS13) ELISA Kit

[ADAM metallopeptidase with ombospondin type 1 motif]

[ADAM metallopeptidase with thrombospondin type 1 motif, 9; A disintegrin and metalloproteinase with thrombospondin motifs 9; A disintegrin and metalloproteinase with thrombospondin motifs 9; ADAM metallopeptidase with thrombospondin type 1 motif 9]

[ADAMTS13]

[ADAMTS9; ADAMTS9; KIAA1312; ADAM-TS 9; ADAM-TS9; ADAMTS-9]

ATS9_HUMAN

Canine

1935

No cross-reaction with other factors.

Store all reagents at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

Samples: Canine Serum, Plasma Or Cell Culture Supernatant And Organizations In The Natural And Recombinant Acrp30 Concentration. Assay Type: Sandwich. Detection Range: 100 ng/ml-1.56 ng/ml. Sensitivity: 0.5 ng/ml.

Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%

Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Canine Acrp30 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

120659948

AAI30579.1

213,420 Da

Degradation Of The Extracellular Matrix Pathway (1270257); Extracellular Matrix Organization Pathway (1270244); Metabolism Of Proteins Pathway (1268677); O-glycosylation Of TSR Domain-containing Proteins Pathway (1268735); O-linked Glycosylation Pathway (1268734); Post-translational Protein Modification Pathway (1268701)

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. Members of the ADAMTS family have been implicated in the cleavage of proteoglycans, the control of organ shape during development, and the inhibition of angiogenesis. This gene is localized to chromosome 3p14.3-p14.2, an area known to be lost in hereditary renal tumors. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016]

ADAMTS9: Cleaves the large aggregating proteoglycans, aggrecan and versican. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Extracellular matrix; Motility/polarity/chemotaxis; Protease; Secreted; EC 3.4.24.-; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 3p14.1. Cellular Component: endoplasmic reticulum; extracellular matrix; proteinaceous extracellular matrix. Molecular Function: metalloendopeptidase activity; metallopeptidase activity; zinc ion binding. Biological Process: glycoprotein catabolic process; multicellular organismal development; protein transport; proteolysis; vesicle-mediated transport

48-Strip-Wells

275 USD

96-Strip-Wells

435

5x96-Strip-Wells

1755

10x96-Strip-Wells

3150