catalog number :
MBS2603013
products type :
ELISA Kit
products full name :
Rat Transcription factor Sp1, SP1 ELISA Kit
products short name :
Sp1 transcription factor
other names :
transcription factor Sp1; Transcription factor Sp1; transcription factor Sp1; trans-acting transcription factor 1; Sp1 transcription factor
other gene names :
Sp1; Sp1
uniprot entry name :
SP1_RAT
storage stability :
Store all reagents at 2-8 degree C.
ncbi acc num :
NP_036787.2
ncbi gb acc num :
NM_012655.2
ncbi mol weight :
80,772 Da
ncbi pathways :
Adipogenesis Pathway 198479!!Androgen Receptor Signaling Pathway 198529!!EGFR1 Signaling Pathway 198427!!Huntington's Disease Pathway 83492!!Huntington's Disease Pathway 512!!Mitochondrial Gene Expression Pathway 219797!!Myometrial Relaxation And Contraction Pathways 198465!!Oxidative Stress Pathway 198512!!SIDS Susceptibility Pathways 219790!!Selenium Metabolism Selenoproteins Pathway 219789
ncbi summary :
transcription factor that recognizes 5'-CCGCCC promoter sequence; plays a role in transcriptional regulation of many genes [RGD, Feb 2006]
uniprot summary :
Function: Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays an essential role in the regulation of FE65 gene expression. Positively regulates the transcription of the core clock component ARNTL/BMAL1 Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter.1 PublicationManual assertion based on experiment in:Ref.3