catalog number :
MBS2603012
products type :
ELISA Kit
products full name :
Human 2, 4-dienoyl-CoA reductase, mitochondrial, DECR1 ELISA Kit
products short name :
2, 4-dienoyl CoA reductase 1, mitochondrial
other names :
2,4-dienoyl-CoA reductase, mitochondrial; 2,4-dienoyl-CoA reductase, mitochondrial; 2,4-dienoyl-CoA reductase, mitochondrial; 4-enoyl-CoA reductase; short chain dehydrogenase/reductase family 18C, member 1; 2,4-dienoyl CoA reductase 1, mitochondrial; 2,4-dienoyl-CoA reductase [NADPH]; 4-enoyl-CoA reductase [NADPH]
other gene names :
DECR1; DECR1; DECR; NADPH; SDR18C1; DECR; 4-enoyl-CoA reductase [NADPH]
uniprot entry name :
DECR_HUMAN
specificity :
No cross-reaction with other factors.
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Samples: Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant DECR1 concentration. Assay Type: Sandwich. Detection Range: 20 ng/ml-0.312 ng/ml. Sensitivity: 0.06 ng/ml.
other info2 :
Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%
products description :
. Principle of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human DECR1 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
ncbi acc num :
NP_001350.1
ncbi gb acc num :
NM_001359.1
ncbi mol weight :
36,068 Da
ncbi pathways :
Fatty Acid Beta Oxidation Pathway (198865); Fatty Acid Biosynthesis Pathway (198873); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Mitochondrial Fatty Acid Beta-Oxidation Pathway (106122); Mitochondrial Fatty Acid Beta-oxidation Of Unsaturated Fatty Acids Pathway (106131)
ncbi summary :
This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters. [provided by RefSeq, Jul 2008]
uniprot summary :
DECR1: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily. Protein type: Oxidoreductase; EC 1.3.1.34; Mitochondrial. Chromosomal Location of Human Ortholog: 8q21.3. Cellular Component: nucleoplasm; mitochondrion; mitochondrial matrix; cytoplasm; nucleus. Molecular Function: oxidoreductase activity, acting on NADH or NADPH; 2,4-dienoyl-CoA reductase (NADPH) activity. Biological Process: fatty acid beta-oxidation; cellular lipid metabolic process; protein homotetramerization