ELISA/assay

Human Sodium- and chloride-dependent taurine transporter, SLC6A6/TAUT ELISA Kit

MBS2602966

48-Strip-Wells

275 USD

ELISA Kit

Human Sodium- and chloride-dependent taurine transporter, SLC6A6/TAUT ELISA Kit

solute carrier family 6 (neurotransmitter transporter, taurine) , member 6

sodium- and chloride-dependent taurine transporter isoform c; Sodium- and chloride-dependent taurine transporter; sodium- and chloride-dependent taurine transporter; solute carrier family 6 (neurotransmitter transporter, taurine), member 6; solute carrier family 6 (neurotransmitter transporter), member 6; Solute carrier family 6 member 6

SLC6A6; SLC6A6; TAUT

SC6A6_HUMAN

Human

No cross-reaction with other factors.

Store all reagents at 2-8 degree C.

Samples: Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant SLC6A6/TAUT concentration. Assay Type: Sandwich. Detection Range: 100 ng/ml-1.56 ng/ml. Sensitivity: 0.5 ng/ml.

Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%

Principle of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human SLC6A6/TAUT monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

618857458

NP_001127839.2

NM_001134367.3

P31641

69,830 Da

Amino Acid Transport Across The Plasma Membrane Pathway (106170); Na+/Cl- Dependent Neurotransmitter Transporters Pathway (161070); SLC-mediated Transmembrane Transport Pathway (119558); Transmembrane Transport Of Small Molecules Pathway (106572); Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway (119571); Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway (119559)

This gene encodes a multi-pass membrane protein that is a member of a family of sodium and chloride-ion dependent transporters. The encoded protein transports taurine and beta-alanine. There is a pseudogene for this gene on chromosome 21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

TAUT: Required for the uptake of taurine. Transports both taurine and beta-alanine which requires sodium ions. Chloride ions are necessary for optimal uptake. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily. Protein type: Transporter, SLC family; Membrane protein, integral; Transporter; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 3p25.1. Cellular Component: integral to plasma membrane; integral to membrane; plasma membrane. Molecular Function: neurotransmitter:sodium symporter activity; taurine binding; taurine:sodium symporter activity. Biological Process: amino acid metabolic process; taurine transport; amino acid transport; transport; neurotransmitter transport; ion transport; transmembrane transport

48-Strip-Wells

275 USD

96-Strip-Wells

420