catalog number :
MBS2602957
products type :
ELISA Kit
products full name :
Human Sodium/bile acid cotransporter, SLC10A1 ELISA Kit
products short name :
solute carrier family 10 (sodium/bile acid cotransporter family) , member 1
other names :
sodium/bile acid cotransporter; Sodium/bile acid cotransporter; sodium/bile acid cotransporter; growth-inhibiting protein 29; Na(+)/bile acid cotransporter; sodium/taurocholate cotransporter; solute carrier family 10 member 1; Na(+)/taurocholate transport protein; cell growth-inhibiting gene 29 protein; Na/taurocholate cotransporting polypeptide; sodium/taurocholate cotransporting polypeptide; solute carrier family 10 (sodium/bile acid cotransporter family), member 1; solute carrier family 10 (sodium/bile acid cotransporter), member 1; Cell growth-inhibiting gene 29 protein; Na(+)/bile acid cotransporter; Na(+)/taurocholate transport protein; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 member 1
other gene names :
SLC10A1; SLC10A1; NTCP; NTCP; GIG29
uniprot entry name :
NTCP_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
ncbi acc num :
NP_003040.1
ncbi gb acc num :
NM_003049.3
ncbi mol weight :
38,119 Da
ncbi pathways :
Bile Acid And Bile Salt Metabolism Pathway 106144!!Bile Secretion Pathway 193146!!Bile Secretion Pathway 193095!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!Recycling Of Bile Acids And Salts Pathway 106149
ncbi summary :
The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis. [provided by RefSeq, Oct 2011]
uniprot summary :
Function: The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium.