product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Dual Specificity Plaosplaatase, DUSP-1 ELISA Kit
catalog :
MBS2602858
quantity :
96 Strip Wells
price :
420 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2602858
products type :
ELISA Kit
products full name :
Human Dual Specificity Plaosplaatase, DUSP-1 ELISA Kit
products short name :
dual specificity phosphatase 1
other names :
dual specificity protein phosphatase 1; Dual specificity protein phosphatase 1; dual specificity protein phosphatase 1; MAP kinase phosphatase 1; protein-tyrosine phosphatase CL100; dual specificity protein phosphatase hVH1; serine/threonine specific protein phosphatase; mitogen-activated protein kinase phosphatase 1; dual specificity phosphatase 1; Dual specificity protein phosphatase hVH1; Mitogen-activated protein kinase phosphatase 1; MAP kinase phosphatase 1; MKP-1; Protein-tyrosine phosphatase CL100
other gene names :
DUSP1; DUSP1; HVH1; MKP1; CL100; MKP-1; PTPN10; CL100; MKP1; PTPN10; VH1; MAP kinase phosphatase 1; MKP-1
uniprot entry name :
DUS1_HUMAN
reactivity :
Human
storage stability :
Store all reagents at 2-8 degree C.
ncbi gi num :
4758204
ncbi acc num :
NP_004408.1
ncbi gb acc num :
NM_004417.3
uniprot acc num :
P28562
ncbi mol weight :
39,298 Da
ncbi pathways :
ATF-2 Transcription Factor Network Pathway 138006!!Direct P53 Effectors Pathway 137939!!EGFR1 Signaling Pathway 198782!!ErbB1 Downstream Signaling Pathway 138057!!Fc-epsilon Receptor I Signaling In Mast Cells Pathway 138050!!MAPK Signaling Pathway 198779!!MAPK Signaling Pathway 83048!!MAPK Signaling Pathway 456!!Regulation Of P38-alpha And P38-beta Pathway 137964!!Serotonergic Synapse Pathway 525336
ncbi summary :
The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle . Catalytic activity: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
size :
96 Strip Wells
price :
420 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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