product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Mouse Histone-lysine N-methyltransferase EZH2, EZH2 ELISA Kit
catalog :
MBS2602838
quantity :
96 Strip Wells
price :
450 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2602838
products type :
ELISA Kit
products full name :
Mouse Histone-lysine N-methyltransferase EZH2, EZH2 ELISA Kit
products short name :
enhancer of zeste homolog 2 (Drosophila)
other names :
histone-lysine N-methyltransferase EZH2 isoform 1; Histone-lysine N-methyltransferase EZH2; histone-lysine N-methyltransferase EZH2; enhancer of zeste homolog 2 (Drosophila); ENX-1; Enhancer of zeste homolog 2
other gene names :
Ezh2; Ezh2; KMT6; Enx-1; Enx1h; mKIAA4065; Enx1h
uniprot entry name :
EZH2_MOUSE
reactivity :
Mouse
storage stability :
Store all reagents at 2-8 degree C.
ncbi gi num :
226442803
ncbi acc num :
NP_031997.2
ncbi gb acc num :
NM_007971.2
uniprot acc num :
Q61188
ncbi mol weight :
85,292 Da
ncbi pathways :
PluriNetWork Pathway 198307
uniprot summary :
Function: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXA7, HOXB6 and HOXC8. EZH2 can also methylate non-histone proteins such as the transcription factor GATA4 and the nuclear receptor RORA.5 PublicationsManual assertion based on experiment in:Ref.8. Catalytic activity: S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
size :
96 Strip Wells
price :
450 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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