product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human A-kinase anchor protein 10, mitochondrial, AKAP10 ELISA Kit
catalog :
MBS2602826
quantity :
96 Strip Wells
price :
420 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2602826
products type :
ELISA Kit
products full name :
Human A-kinase anchor protein 10, mitochondrial, AKAP10 ELISA Kit
products short name :
A kinase (PRKA) anchor protein 10
other names :
A-kinase anchor protein 10, mitochondrial; A-kinase anchor protein 10, mitochondrial; A-kinase anchor protein 10, mitochondrial; protein kinase A anchoring protein 10; dual specificity A kinase-anchoring protein 2; mitochondrial A kinase PPKA anchor protein 10; A kinase (PRKA) anchor protein 10; Dual specificity A kinase-anchoring protein 2; D-AKAP-2; Protein kinase A-anchoring protein 10; PRKA10
other gene names :
AKAP10; AKAP10; PRKA10; AKAP-10; D-AKAP2; D-AKAP-2; AKAP-10; D-AKAP-2; PRKA10
uniprot entry name :
AKA10_HUMAN
reactivity :
Human
storage stability :
Store all reagents at 2-8 degree C.
ncbi gi num :
21493033
ncbi acc num :
NP_009133.2
ncbi gb acc num :
NM_007202.3
uniprot acc num :
O43572
ncbi mol weight :
73,818 Da
ncbi pathways :
Factors Involved In Megakaryocyte Development And Platelet Production Pathway 187196!!G Protein Signaling Pathways 198849!!Hemostasis Pathway 106028
ncbi summary :
This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins bind to the regulatory subunits of protein kinase A (PKA) and confine the holoenzyme to discrete locations within the cell. The encoded protein is localized to mitochondria and interacts with both the type I and type II regulatory subunits of PKA. Polymorphisms in this gene may be associated with increased risk of arrhythmias and sudden cardiac death. [provided by RefSeq, May 2012]
uniprot summary :
Function: Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase
size :
96 Strip Wells
price :
420 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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