This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Mouse 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase delta-3, PLCD3 ELISA Kit
catalog :
MBS2602820
quantity :
96 Strip Wells
price :
450 USD
product information
catalog number :
MBS2602820
products type :
ELISA Kit
products full name :
Mouse 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase delta-3, PLCD3 ELISA Kit
products short name :
phospholipase C, delta 3
other names :
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3; PLC-delta-3; phospholipase C-delta-3; phosphoinositide phospholipase C-delta-3; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3; phospholipase C, delta 3; Phosphoinositide phospholipase C-delta-3; Phospholipase C-delta-3; PLC-delta-3
other gene names :
Plcd3; Plcd3; mKIAA1964; 2610205J15Rik; Kiaa1964; PLC-delta-3
uniprot entry name :
PLCD3_MOUSE
reactivity :
Mouse
storage stability :
Store all reagents at 2-8 degree C.
ncbi gi num :
258645148
ncbi acc num :
NP_690026.2
ncbi gb acc num :
NM_152813.3
uniprot acc num :
Q8K2J0
ncbi mol weight :
88,607 Da
ncbi pathways :
Calcium Signaling Pathway 83247!!Calcium Signaling Pathway 459!!D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway 542923!!D-myo-inositol-5-phosphate Metabolism Pathway 542897!!Inositol Phosphate Metabolism Pathway 83186!!Inositol Phosphate Metabolism Pathway 1001032!!Inositol Phosphate Metabolism Pathway 362!!Inositol Phosphate Metabolism, PI= PIP2 = Ins(1,4,5)P3 = Ins(1,3,4,5)P4 Pathway 421797!!Inositol Phosphate Metabolism, PI= PIP2 = Ins(1,4,5)P3 = Ins(1,3,4,5)P4 Pathway 468323!!Metabolic Pathways 132962
uniprot summary :
Function: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca2+ from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow.1 PublicationManual assertion based on experiment in:Ref.5. Catalytic activity: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol. Cofactor: Binds 3 calcium ions per subunit. Two of the calcium ions are bound to the C2 domain . Enzyme regulation: Strongly activated by phosphatidic acid. Inhibited by phosphatidylethanolamine (PtdEtn), phosphatidylcholine (PtdCho), sphingomyelin and phosphatidylserine (PtdSer)
size :
96 Strip Wells
price :
450 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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