product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Dynactin subunit 1, DCTN1 ELISA Kit
catalog :
MBS2602807
quantity :
96 Strip Wells
price :
420 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2602807
products type :
ELISA Kit
products full name :
Human Dynactin subunit 1, DCTN1 ELISA Kit
products short name :
dynactin 1 (p150, glued homolog, Drosophila)
other names :
dynactin subunit 1 isoform 3; Dynactin subunit 1; dynactin subunit 1; 150 kDa dynein-associated polypeptide; dynactin 1 (p150, glued homolog, Drosophila); dynactin 1; 150 kDa dynein-associated polypeptide; DAP-150; DP-150; p135; p150-glued
other gene names :
DCTN1; DCTN1; P135; DP-150; DAP-150; DP-150
uniprot entry name :
DCTN1_HUMAN
reactivity :
Human
storage stability :
Store all reagents at 2-8 degree C.
ncbi gi num :
205277392
ncbi acc num :
NP_001128512.1
ncbi gb acc num :
NM_001135040.2
uniprot acc num :
Q14203
ncbi mol weight :
141,695 Da
ncbi pathways :
Activation Of Chaperone Genes By XBP1(S) Pathway 530771!!Activation Of Chaperones By IRE1alpha Pathway 105906!!Cell Cycle Pathway 530733!!Cell Cycle, Mitotic Pathway 105765!!Centrosome Maturation Pathway 105807!!Diabetes Pathways 105902!!Disease Pathway 530764!!G2/M Transition Pathway 105801!!Huntington's Disease Pathway 83100!!Huntington's Disease Pathway 512
ncbi summary :
This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA). [provided by RefSeq, Oct 2008]
uniprot summary :
Function: Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles.
size :
96 Strip Wells
price :
420 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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