catalog number :
MBS2602803
products type :
ELISA Kit
products full name :
Human 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma, AGPAT3 ELISA Kit
products short name :
1-acylglycerol-3-phosphate O-acyltransferase 3
other names :
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma; 1-AGPAT 3; 1-AGP acyltransferase 3; lysophosphatidic acid acyltransferase gamma; lysophosphatidic acid acyltransferase-gamma1; 1-acylglycerol-3-phosphate O-acyltransferase 3; 1-acylglycerol-3-phosphate O-acyltransferase 3; 1-AGP acyltransferase 3; 1-AGPAT 3; Lysophosphatidic acid acyltransferase gamma; LPAAT-gamma
other gene names :
AGPAT3; AGPAT3; LPAAT3; LPAAT-GAMMA1; LPAAT3; UNQ759/PRO1490; 1-AGP acyltransferase 3; 1-AGPAT 3; LPAAT-gamma
uniprot entry name :
PLCC_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
ncbi acc num :
NP_001032642.1
ncbi gb acc num :
NM_001037553.1
ncbi mol weight :
43,381 Da
ncbi pathways :
CDP-diacylglycerol Biosynthesis I Pathway (142255); CDP-diacylglycerol Biosynthesis I Pathway (138606); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Glycerolipid Metabolism Pathway (82986); Glycerolipid Metabolism Pathway (361); Glycerophospholipid Biosynthesis Pathway (645313); Glycerophospholipid Metabolism Pathway (82989); Glycerophospholipid Metabolism Pathway (364); Metabolic Pathways (132956); Metabolism Pathway (477135)
ncbi summary :
The protein encoded by this gene is an acyltransferase that converts lysophosphatidic acid into phosphatidic acid, which is the second step in the de novo phospholipid biosynthetic pathway. The encoded protein may be an integral membrane protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
AGPAT3: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 2.3.1.51; Membrane protein, multi-pass; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - glycerolipid; Membrane protein, integral; Lipid Metabolism - ether lipid; Acetyltransferase. Chromosomal Location of Human Ortholog: 21q22.3. Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane; plasma membrane; nuclear envelope. Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity. Biological Process: phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidic acid biosynthetic process; triacylglycerol biosynthetic process; cellular lipid metabolic process; CDP-diacylglycerol biosynthetic process; phospholipid biosynthetic process