product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Bovine malonyl coenzyme A ELISA Kit
catalog :
MBS2602799
quantity :
48-Strip-Wells
price :
315 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2602799
products type :
ELISA Kit
products full name :
Bovine malonyl coenzyme A ELISA Kit
products short name :
malonyl coenzyme A
other names :
malonyl-CoA decarboxylase, mitochondrial; Malonyl-CoA decarboxylase, mitochondrial; malonyl-CoA decarboxylase, mitochondrial; malonyl coenzyme A decarboxylase; malonyl-CoA decarboxylase
other gene names :
MLYCD; MLYCD; MCD; MCD
uniprot entry name :
DCMC_HUMAN
reactivity :
Bovine
storage stability :
Store all reagents at 2-8 degree C.
ncbi gi num :
110349750
ncbi acc num :
NP_036345.2
ncbi gb acc num :
NM_012213.2
uniprot acc num :
O95822
ncbi mol weight :
50,946 Da
ncbi pathways :
AMPK Signaling Pathway (989139); AMPK Signaling Pathway (992181); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Peroxisomal Lipid Metabolism Pathway (106136); Peroxisome Pathway (131226); Peroxisome Pathway (131126); Propanoate Metabolism Pathway (83004); Propanoate Metabolism Pathway (387)
ncbi summary :
The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency. [provided by RefSeq, Jul 2008]
uniprot summary :
MLYCD: Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids. Defects in MLYCD are the cause of malonyl-CoA decarboxylase deficiency (MLYCD deficiency). MLYCD deficiency is an autosomal recessive disease characterized by abdominal pain, chronic constipation, episodic vomiting, metabolic acidosis and malonic aciduria. Protein type: Lyase; Carbohydrate Metabolism - propanoate; EC 4.1.1.9; Other Amino Acids Metabolism - beta-alanine. Chromosomal Location of Human Ortholog: 16q24. Cellular Component: peroxisomal matrix; mitochondrion; mitochondrial matrix; cytoplasm; peroxisome. Molecular Function: receptor binding; malonyl-CoA decarboxylase activity. Biological Process: positive regulation of fatty acid oxidation; acetyl-CoA biosynthetic process; cellular lipid metabolic process; fatty acid biosynthetic process. Disease: Malonyl-coa Decarboxylase Deficiency
size1 :
48-Strip-Wells
price1 :
315 USD
size2 :
96-Strip-Wells
price2 :
490
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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