product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Rat suppressors of cytokine signaling 1, SOCS-1 ELISA Kit
catalog :
MBS2602797
quantity :
96 Strip Wells
price :
450 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2602797
products type :
ELISA Kit
products full name :
Rat suppressors of cytokine signaling 1, SOCS-1 ELISA Kit
products short name :
suppressors of cytokine signaling 1 (SOCS-1)
other names :
Suppressor of cytokine signaling 1; Suppressor of cytokine signaling 1; suppressor of cytokine signaling 1; cytokine inducible SH2-containing protein 1; suppressor of cytokine signaling 1
other gene names :
Socs1; Socs1; Cish1; Socs-1; SOCS-1
uniprot entry name :
SOCS1_RAT
reactivity :
Rat
storage stability :
Store all reagents at 2-8 degree C.
ncbi gi num :
20178091
ncbi acc num :
Q9QX78.1
uniprot acc num :
Q9QX78
ncbi mol weight :
23,826 Da
ncbi pathways :
Adaptive Immune System Pathway 1010925!!Adipogenesis Pathway 198479!!Antigen Processing: Ubiquitination Proteasome Degradation Pathway 1010943!!Class I MHC Mediated Antigen Processing Presentation Pathway 1010942!!Cytokine Signaling In Immune System Pathway 1011036!!ECS Complex Pathway 434769!!ECS Complex Pathway 468394!!EGFR1 Signaling Pathway 198427!!EPO Receptor Signaling Pathway 198514!!Growth Hormone Receptor Signaling Pathway 1011053
ncbi summary :
suppressor of cytokine signalling [RGD, Feb 2006]
uniprot summary :
Function: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS1 is involved in negative regulation of cytokines that signal through the JAK/STAT3 pathway. Through binding to JAKs, inhibits their kinase activity. In vitro, also suppresses Tec protein-tyrosine activity Appears to be a major regulator of signaling by interleukin 6 (IL6) and leukemia inhibitory factor (LIF). Regulates interferon-gamma mediated sensory neuron survival. Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recognize JAK2 SOCS1 appears to be a negative regulator in IGF1R signaling pathway
size :
96 Strip Wells
price :
450 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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