catalog number :
MBS2602789
products type :
ELISA Kit
products full name :
Human 1-acylglycerol-3-phosphate O-acyltransferase ABHD5, ABHD5 ELISA Kit
products short name :
abhydrolase domain containing 5
other names :
1-acylglycerol-3-phosphate O-acyltransferase ABHD5; 1-acylglycerol-3-phosphate O-acyltransferase ABHD5; 1-acylglycerol-3-phosphate O-acyltransferase ABHD5; lipid droplet-binding protein CGI-58; abhydrolase domain-containing protein 5; abhydrolase domain containing 5; Abhydrolase domain-containing protein 5; Lipid droplet-binding protein CGI-58
other gene names :
ABHD5; ABHD5; CDS; CGI58; IECN2; NCIE2; NCIE2; CGI-58
uniprot entry name :
ABHD5_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
ncbi acc num :
NP_057090.2
ncbi gb acc num :
NM_016006.4
ncbi mol weight :
39,096 Da
ncbi pathways :
CDP-diacylglycerol Biosynthesis I Pathway 142255!!Hormone-sensitive Lipase (HSL)-mediated Triacylglycerol Hydrolysis Pathway 106121!!Lipid Digestion, Mobilization, And Transport Pathway 106111!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!Phosphatidylglycerol Biosynthesis II (non-plastidic) Pathway 142264!!Triacylglycerol Biosynthesis Pathway 142242
ncbi summary :
The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Lysophosphatidic acid acyltransferase which functions in phosphatidic acid biosynthesis. May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2. Involved in keratinocyte differentiation.3 PublicationsManual assertion based on experiment in:Ref.7. Catalytic activity: Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate.1 PublicationManual assertion based on experiment in:Ref.9