Human 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha, AGPAT1 ELISA Kit | MyBioSource MBS2602772 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha, AGPAT1 ELISA Kit

catalog :

MBS2602772

quantity :

48-Strip-Wells

price :

275 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2602772

products type :

ELISA Kit

products full name :

Human 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha, AGPAT1 ELISA Kit

products short name :

1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)

other names :

1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; 1-AGPAT 1; 1-AGP acyltransferase 1; lysophospholipid acyltransferase; lysophosphatidic acid acyltransferase alpha; 1-acylglycerol-3-phosphate O-acyltransferase 1 (acetoacetly Coenzyme A thiolase); 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha); 1-acylglycerol-3-phosphate O-acyltransferase 1; 1-acylglycerol-3-phosphate O-acyltransferase 1; 1-AGP acyltransferase 1; 1-AGPAT 1; Lysophosphatidic acid acyltransferase alpha; LPAAT-alpha; Protein G15

other gene names :

AGPAT1; AGPAT1; G15; LPAATA; 1-AGPAT1; LPAAT-alpha; G15; 1-AGP acyltransferase 1; 1-AGPAT 1; LPAAT-alpha

uniprot entry name :

PLCA_HUMAN

reactivity :

Human

specificity :

No cross-reaction with other factors.

storage stability :

Store all reagents at 2-8 degree C.

other info1 :

Samples: Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant AGPAT1 concentration. Assay Type: Sandwich. Detection Range: 20 ng/ml-0.312 ng/ml. Sensitivity: 0.06 ng/ml.

other info2 :

Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%

products description :

Principle of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human AGPAT1 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

ncbi gi num :

5453718

ncbi acc num :

NP_006402.1

ncbi gb acc num :

NM_006411.3

uniprot acc num :

Q99943

ncbi mol weight :

31,717 Da

ncbi pathways :

CDP-diacylglycerol Biosynthesis I Pathway (142255); CDP-diacylglycerol Biosynthesis I Pathway (138606); ChREBP Activates Metabolic Gene Expression Pathway (106104); Fat Digestion And Absorption Pathway (194385); Fat Digestion And Absorption Pathway (194324); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Glycerolipid Metabolism Pathway (82986); Glycerolipid Metabolism Pathway (361); Glycerophospholipid Metabolism Pathway (82989); Glycerophospholipid Metabolism Pathway (364)

ncbi summary :

This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

uniprot summary :

AGPAT1: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. Protein type: Lipid Metabolism - glycerophospholipid; Lipid Metabolism - ether lipid; Membrane protein, integral; Membrane protein, multi-pass; EC 2.3.1.51; Lipid Metabolism - glycerolipid; Transferase. Chromosomal Location of Human Ortholog: 6p21.3. Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane. Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity. Biological Process: positive regulation of cytokine production; phospholipid metabolic process; glycerophospholipid biosynthetic process; positive regulation of cellular metabolic process; energy reserve metabolic process; phosphatidic acid biosynthetic process; triacylglycerol biosynthetic process; cellular lipid metabolic process; positive regulation of cytokine and chemokine mediated signaling pathway; CDP-diacylglycerol biosynthetic process

size1 :

48-Strip-Wells

price1 :

275 USD

size2 :

96-Strip-Wells

price2 :

420

more info or order :

MyBioSource product webpage