product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Rat Type-2 angiotensin II receptor, AGTR2 ELISA Kit
catalog :
MBS2602755
quantity :
48-Strip-Wells
price :
290 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2602755
products type :
ELISA Kit
products full name :
Rat Type-2 angiotensin II receptor, AGTR2 ELISA Kit
products short name :
Type-2 angiotensin II receptor, AGTR2
other names :
type-2 angiotensin II receptor; Type-2 angiotensin II receptor; type-2 angiotensin II receptor; AT2; angiotensin receptor 2; angiotensin II type 2 receptor; angiotensin II type-2 receptor; angiotensin II receptor, type 2; Angiotensin II type-2 receptor; AT2
products gene name :
AGTR2
other gene names :
Agtr2; Agtr2; AT2R; AT2-R; AT sub /sub AT2
uniprot entry name :
AGTR2_RAT
reactivity :
Rat
specificity :
No cross-reaction with other factors.
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Samples: Rat serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant AGTR2 concentration. Assay Type: Sandwich. Detection Range: 10 ng/ml-0.156 ng/ml. Sensitivity: 0.05 ng/ml.
other info2 :
Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%
products description :
Principle of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Rat AGTR2 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
ncbi gi num :
6978473
ncbi acc num :
NP_036626.1
ncbi gb acc num :
NM_012494.3
uniprot acc num :
P35351
ncbi mol weight :
41,331 Da
ncbi pathways :
ACE Inhibitor Pathway (198448); GPCRs, Class A Rhodopsin-like Pathway (198500); Neuroactive Ligand-receptor Interaction Pathway (83445); Neuroactive Ligand-receptor Interaction Pathway (462); Peptide GPCRs Pathway (198538); Renin-angiotensin System Pathway (83467); Renin-angiotensin System Pathway (486)
ncbi summary :
receptor for angiotensin II; vasodilator that regulates many actions in vascular smooth muscle cells and during development [RGD, Feb 2006]
uniprot summary :
AT2: Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. Defects in AGTR2 are the cause of mental retardation X- linked type 88 (MRX88). Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1. Cellular Component: perinuclear region of cytoplasm; integral to membrane; plasma membrane; intracellular. Molecular Function: protein binding; angiotensin type II receptor activity; peptide hormone binding; G-protein alpha-subunit binding; transcription factor binding. Biological Process: positive regulation of phosphoprotein phosphatase activity; negative regulation of icosanoid secretion; regulation of transcription factor import into nucleus; negative regulation of heart rate; negative regulation of nerve growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; renin-angiotensin regulation of aldosterone production; dopamine biosynthetic process; positive regulation of vasodilation; neuron differentiation; angiotensin mediated vasodilation involved in regulation of systemic arterial blood pressure; cerebellar cortex development; cell surface receptor linked signal transduction; regulation of systemic arterial blood pressure by circulatory renin-angiotensin; positive regulation of cell proliferation; negative regulation of neuron apoptosis; kidney development; inflammatory response; cellular sodium ion homeostasis; positive regulation of nitric-oxide synthase activity; response to organic nitrogen; brain renin-angiotensin system; negative regulation of fibroblast proliferation; G-protein signaling, coupled to cGMP nucleotide second messenger; positive regulation of cytokine secretion
size1 :
48-Strip-Wells
price1 :
290 USD
size2 :
96-Strip-Wells
price2 :
450
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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