catalog number :
MBS2602750
products type :
ELISA Kit
products full name :
Human Septin-9, SEPT9 ELISA Kit
products short name :
Septin-9, SEPT9
other names :
septin-9 isoform a; Septin-9; septin-9; septin D1; Ov/Br septin; ovarian/breast septin; MLL septin-like fusion protein MSF-A; septin 9; MLL septin-like fusion protein MSF-A; MLL septin-like fusion protein; Ovarian/Breast septin; Ov/Br septin; Septin D1
products gene name :
9-Sep
other gene names :
SEPT9; SEPT9; MSF; MSF1; NAPB; SINT1; PNUTL4; SeptD1; AF17q25; KIAA0991; MSF; MLL septin-like fusion protein; Ov/Br septin
uniprot entry name :
SEPT9_HUMAN
specificity :
No cross-reaction with other factors.
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Samples: Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant SEPT9 concentration. Assay Type: Sandwich. Detection Range: 20 ng/ml-0.312 ng/ml. Sensitivity: 0.06 ng/ml.
other info2 :
Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%
products description :
Principle of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human SEPT9 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
ncbi acc num :
NP_001106963.1
ncbi gb acc num :
NM_001113491.1
ncbi mol weight :
65,401 Da
ncbi summary :
This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2009]
uniprot summary :
SEPT9: a member of a family of novel GTP binding proteins that have been implicated in cytokinesis and exocytosis. This family include the cell division control proteins CDC3, CDC10, CDC11. Required for the completion of cytokinesis and suggest a role that is distinct from that of Nedd5. Protein type: Cytoskeletal; Hydrolase; Cell cycle regulation. Chromosomal Location of Human Ortholog: 17q25. Cellular Component: microtubule; perinuclear region of cytoplasm; cytoplasm; stress fiber; actin cytoskeleton. Molecular Function: GTPase activity; protein binding; GTP binding. Biological Process: cell division; protein heterooligomerization; metabolic process; cell cycle. Disease: Amyotrophy, Hereditary Neuralgic