Human Type 2 lactosamine alpha-2, 3-sialyltransferase, ST3GAL6 ELISA Kit | MyBioSource MBS2602747 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Type 2 lactosamine alpha-2, 3-sialyltransferase, ST3GAL6 ELISA Kit

catalog :

MBS2602747

quantity :

48-Strip-Wells

price :

275 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2602747

products type :

ELISA Kit

products full name :

Human Type 2 lactosamine alpha-2, 3-sialyltransferase, ST3GAL6 ELISA Kit

products short name :

Type 2 lactosamine alpha-2, 3-sialyltransferase, ST3GAL6

other names :

type 2 lactosamine alpha-2,3-sialyltransferase isoform 3; Type 2 lactosamine alpha-2,3-sialyltransferase; type 2 lactosamine alpha-2,3-sialyltransferase; alpha2,3-sialyltransferase ST3Gal VI; sialyltransferase 10 (alpha-2,3-sialyltransferase VI); CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI; ST3 beta-galactoside alpha-2,3-sialyltransferase 6; CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI; ST3Gal VI; ST3GalVI; Sialyltransferase 10

products gene name :

ST3GAL6

other gene names :

ST3GAL6; ST3GAL6; SIAT10; ST3GALVI; SIAT10; ST3GalVI

uniprot entry name :

SIA10_HUMAN

reactivity :

Human

specificity :

No cross-reaction with other factors.

storage stability :

Store all reagents at 2-8 degree C.

other info1 :

Samples: Human serum, plasma or cell culture supernatant and organizations in the natural and recombinant ST3GAL6 concentration. Assay Type: Sandwich. Detection Range: 50 ng/ml-0.78 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%

products description :

Intended Uses: This product is suitable for in vitro quantitative detection of human serum, plasma or cell culture supernatant and organizations in the natural and recombinant ST3GAL6 concentration. Principle of the Assay This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human ST3GAL6 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

ncbi gi num :

403225032

ncbi acc num :

NP_001258074.1

ncbi gb acc num :

NM_001271145.1

uniprot acc num :

Q9Y274

ncbi mol weight :

38,214 Da

ncbi pathways :

Asparagine N-linked Glycosylation Pathway (161013); Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway (161014); Disease Pathway (530764); Glycogen Storage Diseases Pathway (980468); Glycosaminoglycan Metabolism Pathway (645297); Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway (82995); Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway (370); Keratan Sulfate Biosynthesis Pathway (645302); Keratan Sulfate/keratin Metabolism Pathway (645301); MPS I - Hurler Syndrome Pathway (685537)

ncbi summary :

The protein encoded by this gene is a member of the sialyltransferase family. Members of this family are enzymes that transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. This protein has high specificity for neolactotetraosylceramide and neolactohexaosylceramide as glycolipid substrates and may contribute to the formation of selectin ligands and sialyl Lewis X, a carbohydrate important for cell-to-cell recognition and a blood group antigen. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Sep 2012]

uniprot summary :

ST3GAL6: Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3- sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1. Belongs to the glycosyltransferase 29 family. Protein type: Membrane protein, integral; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Transferase; EC 2.4.99.-. Chromosomal Location of Human Ortholog: 3q12.1. Cellular Component: Golgi membrane; integral to membrane; integral to Golgi membrane. Biological Process: keratan sulfate metabolic process; glycolipid metabolic process; cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; glycosaminoglycan metabolic process; keratan sulfate biosynthetic process; carbohydrate metabolic process; protein modification process; protein amino acid N-linked glycosylation via asparagine; pathogenesis; post-translational protein modification; oligosaccharide metabolic process

size1 :

48-Strip-Wells

price1 :

275 USD

size2 :

96-Strip-Wells

price2 :

420

more info or order :

MyBioSource product webpage