product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Mouse Importin subunit alpha-3, KPNA3 ELISA Kit
catalog :
MBS2602730
quantity :
48-Strip-Wells
price :
290 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2602730
products type :
ELISA Kit
products full name :
Mouse Importin subunit alpha-3, KPNA3 ELISA Kit
products short name :
Importin subunit alpha-3, KPNA3
other names :
importin subunit alpha-4; Importin subunit alpha-4; importin subunit alpha-4; qip2; importin alpha Q2; importin subunit alpha-3; karyopherin subunit alpha-3; karyopherin (importin) alpha 3; Importin alpha Q2; Qip2; Karyopherin subunit alpha-3
products gene name :
KPNA3
other gene names :
Kpna3; Kpna3; IPOA4; Qip2; Qip2
uniprot entry name :
IMA4_MOUSE
reactivity :
Mouse
specificity :
No cross-reaction with other factors.
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Samples: Mouse serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant KPNA3 concentration. Assay Type: Sandwich. Detection Range: 10 ng/ml-0.156 ng/ml. Sensitivity: 0.05 ng/ml.
other info2 :
Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%
products description :
Priciple of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Mouse KPNA3 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
ncbi gi num :
6680596
ncbi acc num :
NP_032492.1
ncbi gb acc num :
NM_008466.5
uniprot acc num :
O35344
ncbi mol weight :
57,773 Da
ncbi pathways :
TNF-alpha NF-kB Signaling Pathway (198358)
uniprot summary :
KPNA3: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non- classical NLS. Recognizes NLSs of influenza A virus nucleoprotein probably through ARM repeats 7-9. Belongs to the importin alpha family. Protein type: Chaperone; Nuclear import; Karyopherin; Adaptor/scaffold. Cellular Component: cytoplasm; nucleus. Molecular Function: protein C-terminus binding; protein transporter activity. Biological Process: protein transport; transport; protein import into nucleus
size1 :
48-Strip-Wells
price1 :
290 USD
size2 :
96-Strip-Wells
price2 :
450
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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