product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human SUN domain-containing protein 2, UNC84B ELISA Kit
catalog :
MBS2602725
quantity :
48-Strip-Wells
price :
275 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2602725
products type :
ELISA Kit
products full name :
Human SUN domain-containing protein 2, UNC84B ELISA Kit
products short name :
SUN domain-containing protein 2, UNC84B
other names :
SUN domain-containing protein 2 isoform a; SUN domain-containing protein 2; SUN domain-containing protein 2; rab5IP; unc-84 homolog B; nuclear envelope protein; protein unc-84 homolog B; rab5-interacting protein; sad1/unc-84 protein-like 2; Sad1 unc-84 domain protein 2; Sad1 and UNC84 domain containing 2; Protein unc-84 homolog B; Rab5-interacting protein; Rab5IP; Sad1/unc-84 protein-like 2
products gene name :
UNC84B
other gene names :
SUN2; SUN2; UNC84B; FRIGG; KIAA0668; RAB5IP; UNC84B; Rab5IP
uniprot entry name :
SUN2_HUMAN
reactivity :
Human
specificity :
No cross-reaction with other factors.
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Samples: Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant UNC84B concentration. Assay Type: Sandwich. Detection Range: 20 ng/ml-0.312 ng/ml. Sensitivity: 0.06 ng/ml.
other info2 :
Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%
products description :
Priciple of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human UNC84B monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
ncbi gi num :
313760643
ncbi acc num :
NP_001186508.1
ncbi gb acc num :
NM_001199579.1
uniprot acc num :
Q9UH99
ncbi mol weight :
80,311 Da
ncbi pathways :
Cell Cycle Pathway (530733); Chromosome Maintenance Pathway (161048); Meiosis Pathway (477133); Meiotic Synapsis Pathway (477134)
ncbi summary :
SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]
uniprot summary :
SUN2: a nuclear transmembrane protein. Forms part of a membrane-spanning fibrillar complex that interconnects attached meiotic telomeres with cytoplasmic structures. Together with SUN1 connects the nuclear envelope with the centrosome. Interacts with RAB5A. Reportedly expressed in the endosome where it may play a role in endosome fusion and endocytosis. Protein type: Nuclear envelope; Membrane protein, integral. Chromosomal Location of Human Ortholog: 22q13.1. Cellular Component: nuclear membrane; condensed nuclear chromosome; nuclear chromosome, telomeric region; integral to nuclear inner membrane; endosome membrane; nuclear envelope. Molecular Function: identical protein binding; protein binding; microtubule binding; lamin binding. Biological Process: mitotic spindle organization and biogenesis; centrosome localization; nuclear migration along microfilament; nuclear migration; nuclear membrane organization and biogenesis; positive regulation of cell migration
size1 :
48-Strip-Wells
price1 :
275 USD
size2 :
96-Strip-Wells
price2 :
420
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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