catalog number :
MBS2602723
products type :
ELISA Kit
products full name :
Mouse Voltage-dependent anion-selective channel protein 2, VDAC2 ELISA Kit
products short name :
Voltage-dependent anion-selective channel protein 2, VDAC2
other names :
voltage-dependent anion-selective channel protein 2; Voltage-dependent anion-selective channel protein 2; voltage-dependent anion-selective channel protein 2; VDAC-2; VDAC-6; outer mitochondrial membrane protein porin 2; voltage-dependent anion-selective channel protein 6; voltage-dependent anion channel 2; Outer mitochondrial membrane protein porin 2; Voltage-dependent anion-selective channel protein 6; VDAC-6; mVDAC6
products gene name :
VDAC2
other gene names :
Vdac2; Vdac2; Vdac6; mVDAC2; mVDAC6; Vdac6; VDAC-2; mVDAC2; VDAC-6; mVDAC6
uniprot entry name :
VDAC2_MOUSE
specificity :
No cross-reaction with other factors.
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Samples: Mouse serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant VDAC2 concentration. Assay Type: Sandwich. Detection Range: 2000 pg/ml-31.2 pg/ml. Sensitivity: 12 pg/ml.
other info2 :
Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%
products description :
Priciple of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Mouse VDAC2 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
ncbi acc num :
NP_035825.1
ncbi gb acc num :
NM_011695.2
ncbi mol weight :
31,733 Da
ncbi pathways :
Calcium Signaling Pathway (83247); Calcium Signaling Pathway (459); HTLV-I Infection Pathway (373903); HTLV-I Infection Pathway (373889); Huntington's Disease Pathway (83297); Huntington's Disease Pathway (512); Parkinson's Disease Pathway (83295); Creatine-phosphate Energy Transfer Pathway (542932)
uniprot summary :
VDAC2: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation- selective. Interacts with hexokinases. Expressed in all tissues examined. Belongs to the eukaryotic mitochondrial porin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Mitochondrial; Channel, misc. Cellular Component: pore complex; mitochondrial outer membrane; membrane; mitochondrion; mitochondrial inner membrane; integral to membrane; nucleus; myelin sheath. Molecular Function: protein binding; nucleotide binding; voltage-gated anion channel activity; porin activity. Biological Process: transport; ion transport; negative regulation of protein polymerization; transmembrane transport; anion transport