product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Serine/threonine-protein kinase PLK4, PLK4 ELISA Kit
catalog :
MBS2602717
quantity :
48-Strip-Wells
price :
275 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2602717
products type :
ELISA Kit
products full name :
Human Serine/threonine-protein kinase PLK4, PLK4 ELISA Kit
products short name :
Serine/threonine-protein kinase PLK4, PLK4
other names :
serine/threonine-protein kinase PLK4 isoform 2; Serine/threonine-protein kinase PLK4; serine/threonine-protein kinase PLK4; PLK-4; Snk akin kinase; serine/threonine kinase 18; serine/threonine-protein kinase 18; serine/threonine protein kinase SAK; serine/threonine-protein kinase Sak; polo-like kinase 4; Polo-like kinase 4; PLK-4; Serine/threonine-protein kinase 18; Serine/threonine-protein kinase Sak
products gene name :
PLK4
other gene names :
PLK4; PLK4; SAK; STK18; SAK; STK18; PLK-4
uniprot entry name :
PLK4_HUMAN
reactivity :
Human
specificity :
No cross-reaction with other factors.
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Samples: Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant PLK4 concentration. Assay Type: Sandwich. Detection Range: 20 ng/ml-0.312 ng/ml. Sensitivity: 0.06 ng/ml.
other info2 :
Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%
products description :
Priciple of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human PLK4 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
ncbi gi num :
299829210
ncbi acc num :
NP_001177728.1
ncbi gb acc num :
NM_001190799.1
uniprot acc num :
O00444
ncbi mol weight :
108,972 Da
ncbi pathways :
Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); Centrosome Maturation Pathway (105807); G2/M Transition Pathway (105801); Loss Of Nlp From Mitotic Centrosomes Pathway (105811); Loss Of Proteins Required For Interphase Microtubule Organization From The Centrosome Pathway (105810); Mitotic G2-G2/M Phases Pathway (160942); PLK2 And PLK4 Events Pathway (138079); Polo-like Kinase Signaling Events In The Cell Cycle Pathway (138077); Recruitment Of Mitotic Centrosome Proteins And Complexes Pathway (105808)
ncbi summary :
This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
uniprot summary :
PLK4: a kinase of the PLK family. Localizes to centrosomes and the cleavage furrow during cytokinesis. Interacts with the protein kinase Tec. Protein type: Kinase, protein; Nucleolus; Protein kinase, Other; EC 2.7.11.21; Protein kinase, Ser/Thr (non-receptor); Other group; PLK family. Chromosomal Location of Human Ortholog: 4q28. Cellular Component: centriole; centrosome; nucleolus; cytosol; cleavage furrow. Molecular Function: identical protein binding; protein serine/threonine kinase activity; protein binding; ATP binding. Biological Process: organelle organization and biogenesis; positive regulation of centriole replication; centriole replication; mitotic cell cycle; G2/M transition of mitotic cell cycle; protein amino acid phosphorylation. Disease: Microcephaly And Chorioretinopathy, Autosomal Recessive, 2
size1 :
48-Strip-Wells
price1 :
275 USD
size2 :
96-Strip-Wells
price2 :
420
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

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